ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVTTPLHSSP KSSLKSSTTS LRSVHTQSGR MGPSEPKHRT TKSWSIWGGN DEEEPELSNK 

        70         80         90        100        110        120 
NKGKETAQDN SQENDNVSNE GTRLHDNQQT TILKETTRIE KGEKDKKDRN AAIVEKNTRP 

       130        140        150        160        170        180 
RAWPFFWGRN KKDPEPTHNI PTDADNNTLS RLANSLNPAP LTNTYIPYKP DAILIRDKGV 

       190        200        210        220        230        240 
KTAKKLTDDI GNQFPNIVVP SFDILPKQTI WNTVTSTIWK WKTEYWDRRP SSRVREGEEQ 

       250        260        270        280        290        300 
VQHSQNQLKE ETNTVANEAK DEERLEHNRG SLFRVDPWKK INLLSDYQSR PIRVLIVGVH 

       310        320        330        340        350        360 
GFFPTKIIRP FIGEPTGTST KFVTEAEEIV KEYFDQHKVP IEISKIALER EGEIFDRVDF 

       370        380        390        400        410        420 
FYEVMKHWSK EINNSDFIYF VSHSQGCPVT IMLLAKLIKN GIINLDNSQF FNDEIQFCSS 

       430        440        450        460        470        480 
KKIISVLAMA GINNGPFYGA DQTLFVRAYQ TIEKDSLREL FEFQKFDSKQ SQSFIEGLRT 

       490        500        510        520        530        540 
IISNNVKITF VGSINDQLVP LYSSTCLFAN HPNIFRAIFI DRGSQTPAFI TRIVKIAGSL 

       550        560        570        580        590        600 
LNLGYNDHGI IKEISGSLAG TLTGGGHSTI YNEKQVYHLG IKFALETTDL SEMYPIEYSP 

       610        620        630        640        650        660 
YKLSELGANP YRLPWCMRGL MYESNKHFSN EEIKMLFKEF EEWEPETKQL KDIKNRLNGL 


KYRL 

References and documentation are available.

Number of amino acids: 664

Molecular weight: 76138.09

Theoretical pI: 8.06

Amino acid composition: 
Ala (A)  25	  3.8%
Arg (R)  33	  5.0%
Asn (N)  46	  6.9%
Asp (D)  32	  4.8%
Cys (C)   4	  0.6%
Gln (Q)  25	  3.8%
Glu (E)  53	  8.0%
Gly (G)  37	  5.6%
His (H)  16	  2.4%
Ile (I)  54	  8.1%
Leu (L)  49	  7.4%
Lys (K)  54	  8.1%
Met (M)   9	  1.4%
Phe (F)  33	  5.0%
Pro (P)  34	  5.1%
Ser (S)  53	  8.0%
Thr (T)  47	  7.1%
Trp (W)  12	  1.8%
Tyr (Y)  19	  2.9%
Val (V)  29	  4.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 85
Total number of positively charged residues (Arg + Lys): 87

Atomic composition:

Carbon      C	      3406
Hydrogen    H	      5316
Nitrogen    N	       932
Oxygen      O	      1025
Sulfur      S	        13

Formula: C3406H5316N932O1025S13
Total number of atoms: 10692

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    94560
Abs 0.1% (=1 g/l)   1.242, assuming all pairs of Cys residues form cystines


Ext. coefficient    94310
Abs 0.1% (=1 g/l)   1.239, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.30
This classifies the protein as stable.



Aliphatic index: 76.93

Grand average of hydropathicity (GRAVY): -0.634