ProtParam
User-provided sequence:
10 20 30 40 50 60
MVVHILGKGF KGKEVIKIAL ASKFYGIGKT TAEKICSKLG FYPWMRMHQL SEPQIMSIAS
70 80 90 100 110 120
ELSTMTIEGD ARAIVKDNIA LKRKIGSYSG MRHTLHLPVR GQHTRNNAKT ARKLNKIDRR
130 140
GIHTFSQAKV QHNPSLWSCI FGK
References and
documentation are available.
Number of amino acids: 143
Molecular weight: 16088.96
Theoretical pI: 10.43
Total number of negatively charged residues (Asp + Glu): 8
Total number of positively charged residues (Arg + Lys): 25
Atomic composition:
Carbon C 717
Hydrogen H 1170
Nitrogen N 212
Oxygen O 192
Sulfur S 8
Formula: C
717H
1170N
212O
192S
8
Total number of atoms: 2299
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 15595
Abs 0.1% (=1 g/l) 0.969, assuming all pairs of Cys residues form cystines
Ext. coefficient 15470
Abs 0.1% (=1 g/l) 0.962, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 45.41
This classifies the protein as unstable.
Aliphatic index: 84.62
Grand average of hydropathicity (GRAVY): -0.315