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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVVHILGKGF KGKEVIKIAL ASKFYGIGKT TAEKICSKLG FYPWMRMHQL SEPQIMSIAS

70 80 90 100 110 120
ELSTMTIEGD ARAIVKDNIA LKRKIGSYSG MRHTLHLPVR GQHTRNNAKT ARKLNKIDRR

130 140
GIHTFSQAKV QHNPSLWSCI FGK


References and documentation are available.

Number of amino acids: 143 Molecular weight: 16088.96 Theoretical pI: 10.43
Amino acid composition: 
Ala (A) 10 7.0% Arg (R) 9 6.3% Asn (N) 5 3.5% Asp (D) 3 2.1% Cys (C) 2 1.4% Gln (Q) 5 3.5% Glu (E) 5 3.5% Gly (G) 12 8.4% His (H) 7 4.9% Ile (I) 14 9.8% Leu (L) 10 7.0% Lys (K) 16 11.2% Met (M) 6 4.2% Phe (F) 5 3.5% Pro (P) 4 2.8% Ser (S) 11 7.7% Thr (T) 8 5.6% Trp (W) 2 1.4% Tyr (Y) 3 2.1% Val (V) 6 4.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 8 Total number of positively charged residues (Arg + Lys): 25 Atomic composition: Carbon C 717 Hydrogen H 1170 Nitrogen N 212 Oxygen O 192 Sulfur S 8 Formula: C717H1170N212O192S8 Total number of atoms: 2299 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 15595 Abs 0.1% (=1 g/l) 0.969, assuming all pairs of Cys residues form cystines Ext. coefficient 15470 Abs 0.1% (=1 g/l) 0.962, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.41 This classifies the protein as unstable. Aliphatic index: 84.62 Grand average of hydropathicity (GRAVY): -0.315