ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVVKAIARNS IGRNGVGAFV FPCRKITLQF CNWGGSSEGM RKFLTSKRLD KWGQEFPWIQ 

        70         80         90        100        110        120 
FEVMRKSGHP LLRAEYTNGR EKVICVRNLN IDNVENKLKL LKDSDGDILR RRTKNDNVES 

       130        140 
LNSSVRGIWS PLHAAKRHRI 

References and documentation are available.

Number of amino acids: 140

Molecular weight: 16123.68

Theoretical pI: 10.46

Amino acid composition: 
Ala (A)   6	  4.3%
Arg (R)  15	 10.7%
Asn (N)  11	  7.9%
Asp (D)   6	  4.3%
Cys (C)   3	  2.1%
Gln (Q)   3	  2.1%
Glu (E)   7	  5.0%
Gly (G)  11	  7.9%
His (H)   3	  2.1%
Ile (I)   9	  6.4%
Leu (L)  12	  8.6%
Lys (K)  12	  8.6%
Met (M)   3	  2.1%
Phe (F)   6	  4.3%
Pro (P)   4	  2.9%
Ser (S)  10	  7.1%
Thr (T)   4	  2.9%
Trp (W)   4	  2.9%
Tyr (Y)   1	  0.7%
Val (V)  10	  7.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 13
Total number of positively charged residues (Arg + Lys): 27

Atomic composition:

Carbon      C	       711
Hydrogen    H	      1151
Nitrogen    N	       221
Oxygen      O	       196
Sulfur      S	         6

Formula: C711H1151N221O196S6
Total number of atoms: 2285

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    23615
Abs 0.1% (=1 g/l)   1.465, assuming all pairs of Cys residues form cystines


Ext. coefficient    23490
Abs 0.1% (=1 g/l)   1.457, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 36.53
This classifies the protein as stable.



Aliphatic index: 83.50

Grand average of hydropathicity (GRAVY): -0.543