ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVVKVLVVGG GGREHALAWK LAQSPHIQQV LVAPGNAGTA NGEKISNSEV SVSNHSILAQ 

        70         80         90        100        110        120 
YCKDHQVGLV IVGPEAPLAA GIVDDLTAAG VACFGPSSKA AQLEASKSYS KAFMERHGIP 

       130        140        150        160        170        180 
TARYGSFTDP REACNFIRTA DFPALVVKAS GLAAGKGVIV AADQDEACQA VMDIMKDGAF 

       190        200        210        220        230        240 
GSAGDTVVVE ELLEGEEVSC LCFTDGSSVA PMPPAQDHKR LQDGDLGPNT GGMGAYCPTP 

       250        260        270        280        290        300 
QVSQELLQQI REIVLQKTVD GMREEGSPYV GVLYAGLMLT KQGPKVLEFN CRFGDPECQV 

       310        320        330        340        350        360 
LLPLLKSDLY EVIQNTLEGK LATSAPVWHN DSSAVTVVMA SSGYPGTYAK GVQIKGLSQL 

       370        380        390        400        410        420 
QDMELQVFHA GTALKDGCVV SSGGRVLTVT AVRPALETAL QAANQGVAAI GFPGAVYRRD 

       430        440        450        460        470        480 
IGHRAITHLK QRRGLTYKDS GVDIAAGNKL VETIKPLAKA TSRPGCNAEL GGFAGLFDLK 

       490        500        510        520        530        540 
AAGFVDPILV SGTDGVGTKL KIAQACGRHG GLGQDLVAMC VNDVLAQGAE PLFFLDYFSC 

       550        560        570        580        590        600 
GSLDVDVASS VIGGIAKACE MAGCALLGGE TAEMPGVYSA GEYDLAGFCV GAVERGALLP 

       610        620        630        640        650        660 
RIGDITEGDL LIGVASSGVH SNGFSLVRKV LERANLSYSS PSPFGTSAQT IGEALLTPTK 

       670        680        690        700        710        720 
IYSRLLLPIL RSGAVKAYAH ITGGGLLENI PRVLPQELAV DIDASRWSIP SVFSWLYKEG 

       730        740        750        760        770        780 
GLSEAEMTRT FNCGLGAVLV VSPINAQVVL HQLHAEKTAA WIVGSLAHKQ PGGEPVVVRN 

       790        800        810        820        830        840 
LKHSLLKAEP ACSDGMAVNQ DSSAPHKRTR VGTNLQALID QAKRPSSSAQ IVVVISNRPG 

       850        860        870        880        890        900 
VQGLKRASLA GIQTRVVDHK LYGSRAEFDS TINTVLEEFG VELVCLAGFM RILTGTFVKK 

       910        920        930        940        950        960 
WTGKLLNIHP SLLPSFKGVN AQKQALQAGV RVAGCTVHFV AEEVDAGAII VQEAVPVLVG 

       970        980        990       1000 
DTEDSLCDRI REAEHRAFPT ALELVASGTV RLGNDGHIEW KSPLKNTC 

References and documentation are available.

Number of amino acids: 1008

Molecular weight: 105840.28

Theoretical pI: 6.06

Amino acid composition: 
Ala (A) 112	 11.1%
Arg (R)  41	  4.1%
Asn (N)  27	  2.7%
Asp (D)  46	  4.6%
Cys (C)  23	  2.3%
Gln (Q)  43	  4.3%
Glu (E)  54	  5.4%
Gly (G) 109	 10.8%
His (H)  23	  2.3%
Ile (I)  45	  4.5%
Leu (L) 102	 10.1%
Lys (K)  47	  4.7%
Met (M)  16	  1.6%
Phe (F)  29	  2.9%
Pro (P)  47	  4.7%
Ser (S)  70	  6.9%
Thr (T)  48	  4.8%
Trp (W)   7	  0.7%
Tyr (Y)  19	  1.9%
Val (V) 100	  9.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 100
Total number of positively charged residues (Arg + Lys): 88

Atomic composition:

Carbon      C	      4674
Hydrogen    H	      7513
Nitrogen    N	      1301
Oxygen      O	      1416
Sulfur      S	        39

Formula: C4674H7513N1301O1416S39
Total number of atoms: 14943

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    68185
Abs 0.1% (=1 g/l)   0.644, assuming all pairs of Cys residues form cystines


Ext. coefficient    66810
Abs 0.1% (=1 g/l)   0.631, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.48
This classifies the protein as stable.



Aliphatic index: 96.76

Grand average of hydropathicity (GRAVY): 0.104