ProtParam
User-provided sequence:
10 20 30 40 50 60
MVVLNPNNWH WVDKNTLPWS KDYLNGKLTS LSTVSSDGKS KIELTQVSSI TGDSNVSQRK
70 80 90 100 110 120
GKPICYFDLQ LSMNVKVTNL DTNKDDEDDD GILADGKLEI PEFMHDESDI PILSQGFDAF
130 140 150
DGLVRSEFVP KVVETLLKYQ DDLIKEHSKD IQV
References and
documentation are available.
Number of amino acids: 153
Molecular weight: 17246.34
Theoretical pI: 4.56
Total number of negatively charged residues (Asp + Glu): 27
Total number of positively charged residues (Arg + Lys): 16
Atomic composition:
Carbon C 763
Hydrogen H 1201
Nitrogen N 197
Oxygen O 249
Sulfur S 4
Formula: C
763H
1201N
197O
249S
4
Total number of atoms: 2414
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 20970
Abs 0.1% (=1 g/l) 1.216, assuming all pairs of Cys residues form cystines
Ext. coefficient 20970
Abs 0.1% (=1 g/l) 1.216, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 26.10
This classifies the protein as stable.
Aliphatic index: 89.67
Grand average of hydropathicity (GRAVY): -0.493