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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVVLNPNNWH WVDKNTLPWS KDYLNGKLTS LSTVSSDGKS KIELTQVSSI TGDSNVSQRK

70 80 90 100 110 120
GKPICYFDLQ LSMNVKVTNL DTNKDDEDDD GILADGKLEI PEFMHDESDI PILSQGFDAF

130 140 150
DGLVRSEFVP KVVETLLKYQ DDLIKEHSKD IQV


References and documentation are available.

Number of amino acids: 153 Molecular weight: 17246.34 Theoretical pI: 4.56
Amino acid composition: 
Ala (A) 2 1.3% Arg (R) 2 1.3% Asn (N) 9 5.9% Asp (D) 19 12.4% Cys (C) 1 0.7% Gln (Q) 6 3.9% Glu (E) 8 5.2% Gly (G) 8 5.2% His (H) 3 2.0% Ile (I) 9 5.9% Leu (L) 16 10.5% Lys (K) 14 9.2% Met (M) 3 2.0% Phe (F) 5 3.3% Pro (P) 6 3.9% Ser (S) 15 9.8% Thr (T) 8 5.2% Trp (W) 3 2.0% Tyr (Y) 3 2.0% Val (V) 13 8.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 27 Total number of positively charged residues (Arg + Lys): 16 Atomic composition: Carbon C 763 Hydrogen H 1201 Nitrogen N 197 Oxygen O 249 Sulfur S 4 Formula: C763H1201N197O249S4 Total number of atoms: 2414 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 20970 Abs 0.1% (=1 g/l) 1.216, assuming all pairs of Cys residues form cystines Ext. coefficient 20970 Abs 0.1% (=1 g/l) 1.216, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 26.10 This classifies the protein as stable. Aliphatic index: 89.67 Grand average of hydropathicity (GRAVY): -0.493