ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVVNTIYIAR HGYRSNWLPE GPYPDPLTGI DSDVPLAEHG VQQAKELAHY LLSLDNQPEA 

        70         80         90        100        110        120 
AFASPFYRCL ETVQPIAKLL EIPVYLERGI GEWYRPDRKP VIPVPAGYEI LSKFFPGVIS 

       130        140        150        160        170        180 
QEWDSTLTPN EKGETEQEMY MRFKKFWPLF IERVEKEYPN VECILLVTHA ASKIALGMSL 

       190        200        210        220        230        240 
LGYDNPRMSL NENGDKIRSG SCSLDKYEIL KKSYDTIDET DDQTSFTYIP FSDRKWVLTM 

       250        260        270        280        290        300 
NGNTEFLSSG EEMNWNFDCV AEAGSDADIK KRQMTKKTSS PIPEADDQTE VETVYISVDI 

       310        320        330        340        350        360 
PSGNYKERTE IAKSAILQYS GLETDAPLFR IGNRLYEGSW ERLVGTELAF PNAAHVHKKT 

       370        380        390        400        410        420 
AGLLSPTEEN ETTNAGQSKG SSTANDPNIQ IQEEDVGLPD STNTSRDHTG DKEEVQSEKI 

       430 
YRIKERIVLS NVRPM 

References and documentation are available.

Number of amino acids: 435

Molecular weight: 49146.10

Theoretical pI: 4.83

Amino acid composition: 
Ala (A)  25	  5.7%
Arg (R)  20	  4.6%
Asn (N)  21	  4.8%
Asp (D)  26	  6.0%
Cys (C)   4	  0.9%
Gln (Q)  14	  3.2%
Glu (E)  43	  9.9%
Gly (G)  26	  6.0%
His (H)   7	  1.6%
Ile (I)  28	  6.4%
Leu (L)  34	  7.8%
Lys (K)  26	  6.0%
Met (M)   9	  2.1%
Phe (F)  13	  3.0%
Pro (P)  28	  6.4%
Ser (S)  34	  7.8%
Thr (T)  28	  6.4%
Trp (W)   7	  1.6%
Tyr (Y)  19	  4.4%
Val (V)  23	  5.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 69
Total number of positively charged residues (Arg + Lys): 46

Atomic composition:

Carbon      C	      2181
Hydrogen    H	      3385
Nitrogen    N	       577
Oxygen      O	       690
Sulfur      S	        13

Formula: C2181H3385N577O690S13
Total number of atoms: 6846

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    67060
Abs 0.1% (=1 g/l)   1.365, assuming all pairs of Cys residues form cystines


Ext. coefficient    66810
Abs 0.1% (=1 g/l)   1.359, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.78
This classifies the protein as stable.



Aliphatic index: 76.67

Grand average of hydropathicity (GRAVY): -0.576