ProtParam
User-provided sequence:
10 20 30 40 50 60
MVVQNSPVSS VHTANFSERG SNTRTMTYKN KLTVCFDDIL KVGAEMMMQQ QLKNVQLDSY
70 80 90 100 110 120
LVNGFSQSQQ KLLKEKVKLF HGILDDLETS LSQSSSYLET LTALGKEKEK EREEAEKKRA
130 140 150 160 170 180
EQENMRKVRE QEELKKRQEL EEASQQQQLQ QNSKEKNGLG LNFSTTAPAN TTDANGSKEN
190 200 210 220 230 240
YQELGSLQSS SQTQLENANA ANNGAAFSPL TTTRIQSQQA QPSDVMFNDL NSMDISMFSG
250 260 270 280 290 300
LDSTGFDSTA FNATVDETKG FDDNDSGNNY NDINISSIEN NINNNINSTK NGKDNNNESN
310 320 330 340 350 360
KNNNGDEKNK NNNEDNENNN NSSEKNNNNN NNNNNNNDDN GNNNNNNSGN DNNNTTNNDS
370 380 390 400 410 420
NNKNNSITTG NDNENIVNND LPTTVVSNPG DNPPPADNGE EYLTLNDFND LNIDWSTTGD
430
NGELDLSGFN I
References and
documentation are available.
Number of amino acids: 431
Molecular weight: 47717.59
Theoretical pI: 4.37
Total number of negatively charged residues (Asp + Glu): 66
Total number of positively charged residues (Arg + Lys): 35
Atomic composition:
Carbon C 1972
Hydrogen H 3113
Nitrogen N 603
Oxygen O 758
Sulfur S 10
Formula: C
1972H
3113N
603O
758S
10
Total number of atoms: 6456
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 14440
Abs 0.1% (=1 g/l) 0.303, assuming all pairs of Cys residues form cystines
Ext. coefficient 14440
Abs 0.1% (=1 g/l) 0.303, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 41.48
This classifies the protein as unstable.
Aliphatic index: 54.08
Grand average of hydropathicity (GRAVY): -1.263