ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVVSDGGKRV KLNVGGEIFE TNASTIQSSC PDSLLAALST STSHGSNPVF IDRDPEIFAV 

        70         80         90        100        110        120 
ILNLLRTGRL PANSSGVFSK QELLDEAMYY GVESLLRLAM LPPPLLGFDA SLVSTIVPAA 

       130        140        150        160        170        180 
DGVPSALTAT AGDASLWIAH GGQISVYDWS LSHAGTVRTH LNDITSICRV WGEAAAIGSG 

       190        200        210        220        230        240 
SASGLHFYDL SGGRYIGSTH WTDPEDPRIH KARVAAVADS EGGVFASFDC LHRENSVLQI 

       250        260        270        280        290        300 
DKSTLQVAAV IGQQSGNSAK TTVPEKLRWL PAKGLLVGSA VQRGVFGCSG YIRIWDPRSR 

       310        320        330        340        350        360 
NIVWETNEPG SGRSTRFGDA LADMDVDVED SILFKVCSKS GDLGMADIRK LGEDPWVYMS 

       370        380        390        400        410        420 
DENPGAWKAG DGGGYSVVHC YRKQVLAARG GALEVWSSVK EKTSGDPIRR RNFVDKEDDS 

       430        440        450        460 
KRGMISKIEA GGDRLFVSRE CMEGVEVWET SSFSGVVSVE 

References and documentation are available.

Number of amino acids: 460

Molecular weight: 49278.43

Theoretical pI: 5.32

Amino acid composition: 
Ala (A)  39	  8.5%
Arg (R)  27	  5.9%
Asn (N)  12	  2.6%
Asp (D)  32	  7.0%
Cys (C)   7	  1.5%
Gln (Q)   9	  2.0%
Glu (E)  25	  5.4%
Gly (G)  49	 10.7%
His (H)   9	  2.0%
Ile (I)  23	  5.0%
Leu (L)  37	  8.0%
Lys (K)  18	  3.9%
Met (M)   8	  1.7%
Phe (F)  14	  3.0%
Pro (P)  18	  3.9%
Ser (S)  52	 11.3%
Thr (T)  20	  4.3%
Trp (W)  11	  2.4%
Tyr (Y)   9	  2.0%
Val (V)  41	  8.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 57
Total number of positively charged residues (Arg + Lys): 45

Atomic composition:

Carbon      C	      2165
Hydrogen    H	      3405
Nitrogen    N	       609
Oxygen      O	       677
Sulfur      S	        15

Formula: C2165H3405N609O677S15
Total number of atoms: 6871

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    74285
Abs 0.1% (=1 g/l)   1.507, assuming all pairs of Cys residues form cystines


Ext. coefficient    73910
Abs 0.1% (=1 g/l)   1.500, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 42.14
This classifies the protein as unstable.



Aliphatic index: 85.20

Grand average of hydropathicity (GRAVY): -0.132