ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MVVTFLQDLE VLQDALLNNL QKLSAISRRK ESGESKHDNK DSFAAIANEH NDEEEEIEFE 

        70         80         90        100        110        120 
DLVNIIESKV SDFESVLKCS IVEMTYKYPE LKLQWEKSPR YDQCDKLHIV KLDKQMNEDI 

       130        140        150        160        170        180 
YAQLVEELDF VLQFVDWFYC YRLKVKEILR QHHKRDLAWN DEKRDRAIKF HAVDYDKLHQ 

       190        200        210        220        230        240 
GTSSSSSLTS TSMEKASTRE KLLSKTKQLT NNLVRGNQIL QSGILQSDLN LDELRAQTNS 

       250        260        270        280        290        300 
LTQIDDKYTQ FETVFKKTAD LVKVLENASH QEKRDVYLSL GFLLCCVSWV LWRRIFKLPV 

       310        320        330        340        350        360 
KLGLWLLFKF FKGILVTLGL VKSYAGSSSS LQAPSLVLNA PILATTTTSS ATSVEPFASV 

       370        380 
SAVSSIQRAV DEAVDRIVSH DEL 

References and documentation are available.

Number of amino acids: 383

Molecular weight: 43882.02

Theoretical pI: 5.70

Amino acid composition: 
Ala (A)  22	  5.7%
Arg (R)  16	  4.2%
Asn (N)  15	  3.9%
Asp (D)  27	  7.0%
Cys (C)   5	  1.3%
Gln (Q)  20	  5.2%
Glu (E)  29	  7.6%
Gly (G)   9	  2.3%
His (H)   9	  2.3%
Ile (I)  18	  4.7%
Leu (L)  51	 13.3%
Lys (K)  32	  8.4%
Met (M)   4	  1.0%
Phe (F)  16	  4.2%
Pro (P)   6	  1.6%
Ser (S)  39	 10.2%
Thr (T)  19	  5.0%
Trp (W)   6	  1.6%
Tyr (Y)  10	  2.6%
Val (V)  30	  7.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 56
Total number of positively charged residues (Arg + Lys): 48

Atomic composition:

Carbon      C	      1961
Hydrogen    H	      3120
Nitrogen    N	       522
Oxygen      O	       599
Sulfur      S	         9

Formula: C1961H3120N522O599S9
Total number of atoms: 6211

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    48150
Abs 0.1% (=1 g/l)   1.097, assuming all pairs of Cys residues form cystines


Ext. coefficient    47900
Abs 0.1% (=1 g/l)   1.092, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 46.99
This classifies the protein as unstable.



Aliphatic index: 98.72

Grand average of hydropathicity (GRAVY): -0.300