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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MWKSVCLVLM CVVVTRAQFP RQCMTPEGLR SGTCCPSPTG LANDECGSIS GRGQCVSITA

70 80 90 100 110 120
DRRPHGPQYP HDGRDDRERW PLRFFNRTCQ CNGNFTGFNC GRCRHGLTGP NCDQRITVVR

130 140 150 160 170 180
RNIMQMSADE KRAFVNALDQ AKRTVHPDLV ICTRRFQEIL SPDGASVQVE NITIYNYFVW

190 200 210 220 230 240
THYYSVSKTY MGPGQQSFGG VDFSHEGPGF VTWHRYHLLQ LERDMQDMLG DPSFALPYWN

250 260 270 280 290 300
FAIGGSECDI CTDDLIGARS SFDTNGISSN SVFSQWRVIC ESVEEYETLG TICNNTESSP

310 320 330 340 350 360
IRRNPAGNVA RPMVQRLPEP QDVIDCLELN TFDTPPYYST SSQSFRNTIE GYSAPQGNYD

370 380 390 400 410 420
PVVRSLHNLA HLFLNGTGGQ THLSPNDPIF VLLHTFTDAI FDEWLQRHTA AGTLAYPEEN

430 440 450 460 470 480
APIGHNREFN MVPFWPPIRN AEMFVSAPDN LGYTYEVQWP TRAYTISEII TIAIVAVVLV

490 500 510 520
VAVVGGVIGC AVRARSYRSA EGLEPLLGEQ FRRYSEDERH ASQSVV


References and documentation are available.

Number of amino acids: 526 Molecular weight: 59033.37 Theoretical pI: 5.69
Amino acid composition: 
Ala (A) 30 5.7% Arg (R) 40 7.6% Asn (N) 28 5.3% Asp (D) 27 5.1% Cys (C) 19 3.6% Gln (Q) 24 4.6% Glu (E) 29 5.5% Gly (G) 40 7.6% His (H) 15 2.9% Ile (I) 27 5.1% Leu (L) 33 6.3% Lys (K) 4 0.8% Met (M) 11 2.1% Phe (F) 25 4.8% Pro (P) 34 6.5% Ser (S) 38 7.2% Thr (T) 34 6.5% Trp (W) 9 1.7% Tyr (Y) 19 3.6% Val (V) 40 7.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 56 Total number of positively charged residues (Arg + Lys): 44 Atomic composition: Carbon C 2596 Hydrogen H 3969 Nitrogen N 741 Oxygen O 782 Sulfur S 30 Formula: C2596H3969N741O782S30 Total number of atoms: 8118 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 78935 Abs 0.1% (=1 g/l) 1.337, assuming all pairs of Cys residues form cystines Ext. coefficient 77810 Abs 0.1% (=1 g/l) 1.318, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 52.89 This classifies the protein as unstable. Aliphatic index: 72.24 Grand average of hydropathicity (GRAVY): -0.326