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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MWNPILLDTS SFSFQKHVSG VFLQVRNATK RAAGSRTSMK DSAGRRLGPK KYEGQDVSTG

70 80 90 100 110 120
EIIMRQRGTK FYPGENVGIG KDHSIFALEP GVVRYYLDPF HPKRKFIGVA LRRDLKLPSP

130 140 150 160 170 180
HFEPTVRRFG RFELTNKRAA YKEENSISRK DYLAKPNILK QLEVRESKRK ELQDKLSKVL

190 200 210 220 230 240
RDELKLDIKD IELATSYLIR VRASLKNGYP IEDARFNSRY YLKEEERLKA RRESWTNEKL

250 260 270 280 290 300
SESLSKIDEC SDLLNSSTSF NNKLELHQYI SEQEKQALKA KLLEDLEKSQ HLETKKDKNY

310 320 330 340 350 360
IKALFKDACN FLTLSEEVHL RRKYLKSVFP ETDSTVETKS GKKSIVSRRF DYTKNKVEVI

370
ARSRRAFLSK L


References and documentation are available.

Number of amino acids: 371 Molecular weight: 43226.57 Theoretical pI: 9.82
Amino acid composition: 
Ala (A) 19 5.1% Arg (R) 33 8.9% Asn (N) 15 4.0% Asp (D) 19 5.1% Cys (C) 2 0.5% Gln (Q) 10 2.7% Glu (E) 32 8.6% Gly (G) 15 4.0% His (H) 7 1.9% Ile (I) 17 4.6% Leu (L) 41 11.1% Lys (K) 44 11.9% Met (M) 3 0.8% Phe (F) 17 4.6% Pro (P) 12 3.2% Ser (S) 35 9.4% Thr (T) 16 4.3% Trp (W) 2 0.5% Tyr (Y) 14 3.8% Val (V) 18 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 51 Total number of positively charged residues (Arg + Lys): 77 Atomic composition: Carbon C 1926 Hydrogen H 3111 Nitrogen N 555 Oxygen O 564 Sulfur S 5 Formula: C1926H3111N555O564S5 Total number of atoms: 6161 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 31985 Abs 0.1% (=1 g/l) 0.740, assuming all pairs of Cys residues form cystines Ext. coefficient 31860 Abs 0.1% (=1 g/l) 0.737, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 50.47 This classifies the protein as unstable. Aliphatic index: 80.16 Grand average of hydropathicity (GRAVY): -0.788