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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MYKYTSINKS DKIYETHNME EKKKKGNNNN FSGLLNNEID DNNKKEKLKN SISKMYSNHK

70 80 90 100 110 120
NRENFNECEK EDLVVIDEKD NNKKKKKNMT NTFEQDNNYN MNDNKRLGSF FKINDKCESI

130 140 150 160 170 180
NENVNNINKQ SLKDSILFDN INEKEYFNET KEENKEGNKS NDIEKINCMK VKKKTVKKNK

190 200 210 220 230 240
KKINKIINNK NKISKSNDIE EQIINISKHI YKILNISKLP KCDILKRTNR RYAETFLYLT

250 260 270 280 290 300
NGYNLDIEQI IKRSLYKRMY KNNSIIKVTG IHIYSLCKHH LLPFEGTCDI EYIPNKYIIG

310 320 330 340 350 360
LSKFSRIVDV FSRRLQLQED LTNDICNALK KYLKPLYIKV SIVAKHLCIN MRGVKEHDAK

370 380
TITYASYKAE KENPTVHSLN IDSSVENLN


References and documentation are available.

Number of amino acids: 389 Molecular weight: 45876.53 Theoretical pI: 9.39
Amino acid composition: 
Ala (A) 6 1.5% Arg (R) 11 2.8% Asn (N) 58 14.9% Asp (D) 21 5.4% Cys (C) 8 2.1% Gln (Q) 6 1.5% Glu (E) 31 8.0% Gly (G) 9 2.3% His (H) 9 2.3% Ile (I) 42 10.8% Leu (L) 27 6.9% Lys (K) 64 16.5% Met (M) 8 2.1% Phe (F) 11 2.8% Pro (P) 5 1.3% Ser (S) 26 6.7% Thr (T) 15 3.9% Trp (W) 0 0.0% Tyr (Y) 19 4.9% Val (V) 13 3.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 52 Total number of positively charged residues (Arg + Lys): 75 Atomic composition: Carbon C 2017 Hydrogen H 3268 Nitrogen N 568 Oxygen O 618 Sulfur S 16 Formula: C2017H3268N568O618S16 Total number of atoms: 6487 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 28810 Abs 0.1% (=1 g/l) 0.628, assuming all pairs of Cys residues form cystines Ext. coefficient 28310 Abs 0.1% (=1 g/l) 0.617, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 49.68 This classifies the protein as unstable. Aliphatic index: 80.41 Grand average of hydropathicity (GRAVY): -0.973