ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MYLTKQIPHY SRIHTTQLLT VVNHRTIPFK IRGSFSNCRR YSNFATVPLL ERPFKNKSKH 

        70         80         90        100        110        120 
NTARASRPFS TQKMLLTKSH PPNMYKDSVF FGYRPIVFSG KQDQKSKVIQ CLRTERKTIP 

       130        140        150        160        170        180 
DDLVEDEVDR FYNKLGLDDY YFQMEPVSII ADHIEIIYAA KIAAHASHAK EELNIHVKNE 

       190        200        210        220        230        240 
NEDLAIYLDS SPVTQPELDQ SSAVEESIST RYLDPFKLTD PTAYRVESFT SVTNIDRTST 

       250        260        270        280        290        300 
ENSNIYTYFV TKCDFVDNPK KDASPDVPTD IASVSDKTFL EKASDNTIEM YQDVMNSVLT 

       310        320        330        340        350        360 
RFGPVVRLFD YQGRSEIRLV VGYRRGSIFQ YFPSLSKLFR YYGLHSTRTY VEQFSNGVTI 

       370        380        390        400        410        420 
ISYNFKPELF KNAAVTSINE LFSQITREAS LLYCLPSTDF QPLFVSEKLS IQEVTYAHCV 

       430        440        450        460        470        480 
RIFCEHVMNK LGPEYSSLSA ILDHSNNIHA EILETIKRRL STLAFTRTKI HDTIMQYPGL 

       490        500        510        520        530        540 
VHTLFEQFYL EHAINHNSTP HLHRAKSATS LADEASTYSI TPMSATALMD LIQKTCTNEE 

       550        560        570        580        590        600 
DVSVMEMFVK FNTHLLKTNF FQTTKVALSF RFDPSFLDST QYKDPLYAMI MSIGNEFRGF 

       610        620        630        640        650        660 
HLRFRDVARG GIRLIKSANP EAFGLNARGL FDENYNLAKT QMLKNKDIPE GGAKGVILLG 

       670        680        690        700        710        720 
KDCQDKPELA FMKYIDSIID LLIVNKSQPL VDKLGKPEIL FMGPDENTAD LVNWATIHAH 

       730        740        750        760        770        780 
RRNAPWWKSF FTGKKPTMGG IPHDKYGMTS LSVRCYVEGI YKKLNITDPS KLTKVQTGGP 

       790        800        810        820        830        840 
DGDLGSNEIK LSNEKYIAVI DGSGVLYDPA GLDRTELLRL ADERKTIDHF DAGKLSPEGY 

       850        860        870        880        890        900 
RVLVKDTNLK LPNGEIVRNG TIFRNTAHLR YKADTFVPCG GRPNAININN VEQLIDDHGR 

       910        920        930        940        950        960 
PAFKYLVEGA NLFITQDAKS VLEKAGVIVI RDASANKGGV TSSSLEVLAS LSFDDASFKE 

       970        980        990       1000       1010       1020 
NMCVHDGKVP TFYADYVNEV KRIIQRNANL EFEAIWKGHS ENKIPYTSLS NHLSTEIVKL 

      1030       1040       1050       1060       1070       1080 
DHDIYNYEKL WADVGFRNAV LRASIPKTLQ AKIGLEKMLE RIPESYLRAI FSTYLASRFV 

      1090       1100 
YQHVVSSDPF AFFDYISTEM KMLKDA 

References and documentation are available.

Number of amino acids: 1106

Molecular weight: 125712.29

Theoretical pI: 7.63

Amino acid composition: 
Ala (A)  69	  6.2%
Arg (R)  56	  5.1%
Asn (N)  59	  5.3%
Asp (D)  69	  6.2%
Cys (C)  11	  1.0%
Gln (Q)  30	  2.7%
Glu (E)  63	  5.7%
Gly (G)  51	  4.6%
His (H)  33	  3.0%
Ile (I)  75	  6.8%
Leu (L)  98	  8.9%
Lys (K)  77	  7.0%
Met (M)  23	  2.1%
Phe (F)  61	  5.5%
Pro (P)  50	  4.5%
Ser (S)  87	  7.9%
Thr (T)  73	  6.6%
Trp (W)   5	  0.5%
Tyr (Y)  49	  4.4%
Val (V)  67	  6.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 132
Total number of positively charged residues (Arg + Lys): 133

Atomic composition:

Carbon      C	      5651
Hydrogen    H	      8811
Nitrogen    N	      1511
Oxygen      O	      1669
Sulfur      S	        34

Formula: C5651H8811N1511O1669S34
Total number of atoms: 17676

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   101135
Abs 0.1% (=1 g/l)   0.804, assuming all pairs of Cys residues form cystines


Ext. coefficient   100510
Abs 0.1% (=1 g/l)   0.800, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.18
This classifies the protein as stable.



Aliphatic index: 84.81

Grand average of hydropathicity (GRAVY): -0.328