ProtParam
User-provided sequence:
10 20 30 40 50 60
MYRSSISIQV FICVLFLPLD SGRPLIYMID LSYICSDATV FSGKSRVIFF SNPICEHTRG
70 80 90 100 110 120
NFYLFYLNYI INTFAPKNRG TRRCKPFGLH INCRKKIDCL HVQLSYILCK NKSRKRHMDA
130 140 150
HAHNPCMVST RPHVSEFAKM IVKCVDSSIR GEVGELKVE
References and
documentation are available.
Number of amino acids: 159
Molecular weight: 18357.61
Theoretical pI: 9.48
Total number of negatively charged residues (Asp + Glu): 11
Total number of positively charged residues (Arg + Lys): 23
Atomic composition:
Carbon C 822
Hydrogen H 1300
Nitrogen N 230
Oxygen O 219
Sulfur S 14
Formula: C
822H
1300N
230O
219S
14
Total number of atoms: 2585
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 10930
Abs 0.1% (=1 g/l) 0.595, assuming all pairs of Cys residues form cystines
Ext. coefficient 10430
Abs 0.1% (=1 g/l) 0.568, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 40.07
This classifies the protein as unstable.
Aliphatic index: 89.43
Grand average of hydropathicity (GRAVY): -0.019