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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
PSWSKLTANS QYVSEYTPRG TGLACGTCVL SSDFGFILDC NFKKSGLFRV RNLGGLKAHF

70 80 90 100 110 120
GLGFSLGDEL GFPESLGNTE SDRRRAISYK NGAPPDLVGV LPSTQQQVNP PVQHPLPEKR

130 140 150 160 170 180
ISSRSTGAAP YNLQQVQQQQ QLQLQQQKLQ QQQLQQQLKL KQLLLLQQQQ QQQQQLMTEA

190 200 210 220 230 240
RPLPLGVPAF RPIPQKQLAA TQPSAPSSTP AERRVAVDTP EPRVSVNNKL VSSIDQPHSN

250 260 270 280 290 300
RTFHVANPVV SQPVAVPVFQ AMPQSIARIA NVGKEHRTVS SHPNYLQFEE PKFDLKDVTV

310 320 330 340 350 360
EELAAAANVT VDTIKHAIYV REQQLKAEHR AQLAAKLREE FMRTSTVRTT TTTTTTTTTT

370 380 390 400 410 420
PRPQKSLAEH KVSKVMNAPK EYYPVGYDKN FDDNFKSKVD LPPTSFSCAK QKHFPGLYAD

430 440 450 460 470 480
TDLGCMVFHV CALTDDGMVR KSFLCPENTL FDQTILKCNW WFYVDCSSST SVYDSNIPIS

490 500 510 520 530 540
KSYQLMKSLT YFSKYAGGQR HEQGGDKDEN ALDIDSLRES MEGVARRQEQ AKKAELRVEE

550 560
QRSMPKEDHE HVVPAEAEQQ LSN


References and documentation are available.

Number of amino acids: 563 Molecular weight: 63042.16 Theoretical pI: 8.69
Amino acid composition: 
Ala (A) 40 7.1% Arg (R) 29 5.2% Asn (N) 22 3.9% Asp (D) 26 4.6% Cys (C) 9 1.6% Gln (Q) 55 9.8% Glu (E) 32 5.7% Gly (G) 26 4.6% His (H) 14 2.5% Ile (I) 13 2.3% Leu (L) 50 8.9% Lys (K) 35 6.2% Met (M) 9 1.6% Phe (F) 22 3.9% Pro (P) 39 6.9% Ser (S) 46 8.2% Thr (T) 37 6.6% Trp (W) 3 0.5% Tyr (Y) 15 2.7% Val (V) 41 7.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 58 Total number of positively charged residues (Arg + Lys): 64 Atomic composition: Carbon C 2769 Hydrogen H 4385 Nitrogen N 793 Oxygen O 855 Sulfur S 18 Formula: C2769H4385N793O855S18 Total number of atoms: 8820 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 39350 Abs 0.1% (=1 g/l) 0.624, assuming all pairs of Cys residues form cystines Ext. coefficient 38850 Abs 0.1% (=1 g/l) 0.616, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is P (Pro). The estimated half-life is: >20 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). ? (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 55.75 This classifies the protein as unstable. Aliphatic index: 71.87 Grand average of hydropathicity (GRAVY): -0.618