ProtParam

User-provided sequence:

        10         20         30         40         50         60 
TKHEPVYKPV KTSYSAPYKP PTYQPLKKKV DYRPTKSYPP TYGSKTNYLP LAKKLSSYKP 

        70         80         90        100        110        120 
IKTTYNAKTN YPPVYKPKMT YPPTYKPKPS YPPTYKSKPT YKPKITYPPT YKAKPSYPSS 

       130        140        150        160        170        180 
YKPKKTYPPT YKPKLTYPPT YKPKPSYPPT YKPKPSYPPS YKTKKTYPSS YKAKPSYPPT 

       190        200        210        220        230        240 
YKAKPSYPPT YKAKPSYPPT YKAKPTYKAK PTYPSTYKAK PSYPPTYKAK PTYKAKPSYP 

       250        260        270        280        290        300 
PTYKAKPSYP PTYKAKPSYP PTYKAKPTYK AKPTYKAKPT YKAKPSYPPT YKAKPSYPPT 

       310        320        330        340        350        360 
YKAKPSYPPT YKAKPSYPPT YKAKPSYPPT YKAKPSYPPT YKAKPTYKAK PTYPSTYKAK 

       370        380        390        400        410        420 
PSYPPTYKAK PSYPPTYKAK PTYKAKPSYP PTYKAKPSYP PTYKAKPSYP PTYKAKPTYK 

       430        440        450        460        470        480 
AKPTYPSTYK AKPSYPPSYK AKPSYPPTYK AKPTYKAKPT YPSTYKAKPS YPASYKAKPS 

       490        500        510        520        530        540 
YPPTYKSKSS YPSSYKPKKT YPPTYKPKLT YKPTYKPKPS YPPSYKPKTT YPPTYKPKIS 

       550        560        570        580        590        600 
YPPTYKAKPS YPATYKAKPS YPPTYKAKPS YPPTYKAKPS YPPTYKAKPS YKAKPTYPST 

       610        620        630        640        650        660 
YKAKPSYPPT YKAKPSYPPT YKAKPSYPPT YKAKPTYPST YKAKPSYPPT YKPKISYPPT 

       670        680        690        700        710        720 
YKAKPSYPPT YKAKPSYPPT YKAKPTYKAK PTNPSTYKAK PSYPPTYKAK PSYPPTYKAK 

       730        740        750        760        770        780 
PSYPPTYKAK PTYKAKPTYP STYKAKPTYK AKPTYPPTYK AKPSYPPTYK PKPSYPPTYK 

       790        800        810        820        830        840 
SKSIYPSSYK PKKTYPPTYK PKLTYPPTYK PKPSYPPSYK PKITYPSTYK LKPSYPPTYK 

       850        860        870 
SKTSYPPTYN KKISYPSSYK AKTSYPPAYK PTNRY 

References and documentation are available.

Number of amino acids: 875

Molecular weight: 100412.69

Theoretical pI: 10.05

Amino acid composition: 
Ala (A)  66	  7.5%
Arg (R)   2	  0.2%
Asn (N)   6	  0.7%
Asp (D)   1	  0.1%
Cys (C)   0	  0.0%
Gln (Q)   1	  0.1%
Glu (E)   1	  0.1%
Gly (G)   1	  0.1%
His (H)   1	  0.1%
Ile (I)   7	  0.8%
Leu (L)   8	  0.9%
Lys (K) 190	 21.7%
Met (M)   1	  0.1%
Phe (F)   0	  0.0%
Pro (P) 224	 25.6%
Ser (S)  87	  9.9%
Thr (T) 107	 12.2%
Trp (W)   0	  0.0%
Tyr (Y) 168	 19.2%
Val (V)   4	  0.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 2
Total number of positively charged residues (Arg + Lys): 192

Atomic composition:

Carbon      C	      4832
Hydrogen    H	      7176
Nitrogen    N	      1080
Oxygen      O	      1249
Sulfur      S	         1

Formula: C4832H7176N1080O1249S1
Total number of atoms: 14338

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   250320
Abs 0.1% (=1 g/l)   2.493

Estimated half-life:

The N-terminal of the sequence considered is T (Thr).

The estimated half-life is: 7.2 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.40
This classifies the protein as unstable.



Aliphatic index: 15.55

Grand average of hydropathicity (GRAVY): -1.494