| Official Name |
|---|
| Phosphoglycerate dehydrogenase.
|
| Alternative Name(s) |
|---|
| 3-phosphoglycerate dehydrogenase. |
| 3-phosphoglyceric acid dehydrogenase. |
| 3PHP reductase. |
| Alpha-KG reductase. |
| Alpha-phosphoglycerate dehydrogenase. |
| D-3-phosphoglycerate dehydrogenase. |
| Glycerate 3-phosphate dehydrogenase. |
| Glycerate-1,3-phosphate dehydrogenase. |
| PGDH. |
| Phosphoglycerate oxidoreductase. |
| Phosphoglyceric acid dehydrogenase. |
| Reaction catalysed |
|---|
|
| Comment(s) |
|---|
- Catalyzes the first committed step in the phosphoserine pathway of
serine biosynthesis in Escherichia coli.
- Reaction (1) occurs predominantly in the reverse direction and is
inhibited by serine and glycine.
- The enzyme is unusual in that it also acts as a D- and L-2-
hydroxyglutarate dehydrogenase (with the D-form being the better
substrate) and as a 2-oxoglutarate reductase.
|
| Cross-references |
|---|
| Biochemical Pathways; map number(s) | D6 |
| PROSITE | PDOC00063 |
| BRENDA | 1.1.1.95 |
| PUMA2 | 1.1.1.95 |
| PRIAM enzyme-specific profiles | 1.1.1.95 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.95 |
| IUBMB Enzyme Nomenclature | 1.1.1.95 |
| IntEnz | 1.1.1.95 |
| MEDLINE | Find literature relating to 1.1.1.95 |
| MetaCyc | 1.1.1.95 |
| UniProtKB/Swiss-Prot |
| P40510, SER33_YEAST; | O04130, SERA_ARATH; | O29445, SERA_ARCFU; |
| P35136, SERA_BACSU; | Q5EAD2, SERA_BOVIN; | Q54UH8, SERA_DICDI; |
| P0A9T2, SERA_ECO57; | P0A9T1, SERA_ECOL6; | P0A9T0, SERA_ECOLI; |
| P43885, SERA_HAEIN; | O43175, SERA_HUMAN; | Q60HD7, SERA_MACFA; |
| Q58424, SERA_METJA; | O27051, SERA_METTH; | Q61753, SERA_MOUSE; |
| P0A545, SERA_MYCBO; | O33116, SERA_MYCLE; | P0A544, SERA_MYCTU; |
| A5A6P1, SERA_PANTR; | A5GFY8, SERA_PIG; | Q5R7M2, SERA_PONAB; |
| O08651, SERA_RAT; | P87228, SERA_SCHPO; | P0A9T3, SERA_SHIFL; |
| P73821, SERA_SYNY3; | P40054, SERA_YEAST; |
|
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