| Official Name |
|---|
| Vitamin-K-epoxide reductase (warfarin-insensitive).
|
| Alternative Name(s) |
|---|
| Vitamin K 2,3-epoxide reductase. |
| Reaction catalysed |
|---|
| 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol |
| Comment(s) |
|---|
- In the reverse reaction, vitamin K 2,3-epoxide is reduced to
3-hydroxy- (and 2-hydroxy-) vitamin K by 1,4-dithioerythritol, which
is oxidized to a disulfide.
- Not inhibited by warfarin (cf. EC 1.1.4.1).
|
| Cross-references |
|---|
| BRENDA | 1.1.4.2 |
| PUMA2 | 1.1.4.2 |
| PRIAM enzyme-specific profiles | 1.1.4.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.4.2 |
| IUBMB Enzyme Nomenclature | 1.1.4.2 |
| IntEnz | 1.1.4.2 |
| MEDLINE | Find literature relating to 1.1.4.2 |
| MetaCyc | 1.1.4.2 |
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