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NiceZyme View of ENZYME: EC 1.1.99.32

Official Name
L-sorbose 1-dehydrogenase.
Alternative Name(s)
SDH.
Reaction catalysed
L-sorbose + acceptor <=> 1-dehydro-L-sorbose + reduced acceptor
Comment(s)
  • The product, 1-dehydro-L-sorbose, is an intermediate in bacterial 2-keto-L-gulonic-acid formation.
  • The activity of this membrane-bound enzyme is stimulated by Fe(III) or Co(2+) but is inhibited by Cu(2+).
  • Highly specific for L-sorbose as other sugars, such as glucose, mannitol and sorbitol, are not substrates.
  • Phenazine methosulfate and DCIP can act as artificial acceptors.
Cross-references
PROSITEPDOC00543
BRENDA1.1.99.32
PUMA21.1.99.32
PRIAM enzyme-specific profiles1.1.99.32
KEGG Ligand Database for Enzyme Nomenclature1.1.99.32
IUBMB Enzyme Nomenclature1.1.99.32
IntEnz1.1.99.32
MEDLINEFind literature relating to 1.1.99.32
MetaCyc1.1.99.32
UniProtKB/Swiss-Prot
Q47944, SDH_GLUOX

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