ID   1.10.99.2
DE   Ribosyldihydronicotinamide dehydrogenase (quinone).
AN   N-ribosyldihydronicotinamide dehydrogenase (quinone).
AN   NAD(P)H:quinone oxidoreductase 2.
AN   NQO(2).
AN   NRH:quinone oxidoreductase 2.
AN   QR2.
AN   Quinone reductase 2.
CA   1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-
CA   ribofuranosyl)nicotinamide + a hydroquinone.
CF   FAD; Zinc.
CC   -!- Unlike EC 1.6.5.2, this quinone reductase cannot use NADH or NADPH;
CC       instead it uses N-ribosyl- and N-alkyldihydronicotinamides.
CC   -!- Polycyclic aromatic hydrocarbons, such as benz[a]anthracene, and the
CC       estrogens 17-beta-estradiol and diethylstilbestrol are potent
CC       inhibitors, but dicoumarol is only a very weak inhibitor.
CC   -!- This enzyme can catalyze both 2-electron and 4-electron reductions,
CC       but one-electron acceptors, such as potassium ferricyanide, cannot be
CC       reduced.
DR   P16083, NQO2_HUMAN ;  Q9JI75, NQO2_MOUSE ;  Q5RBB9, NQO2_PONAB ;
DR   Q6AY80, NQO2_RAT   ;
//