ID   1.13.11.11
DE   Tryptophan 2,3-dioxygenase.
AN   Indolamine 2,3-dioxygenase.
AN   Indoleamine 2,3-dioxygenase.
AN   L-tryptophan 2,3-dioxygenase.
AN   L-tryptophan pyrrolase.
AN   Tryptamin 2,3-dioxygenase.
AN   Tryptamine 2,3-dioxygenase.
AN   Tryptophan oxygenase.
AN   Tryptophan peroxidase.
AN   Tryptophan pyrrolase.
AN   Tryptophanase.
CA   L-tryptophan + O(2) = N-formyl-L-kynurenine.
CF   Heme.
CC   -!- Catalyzes, together with EC 1.13.11.52, the first and rate-limiting
CC       step in the kynurenine pathway, the major pathway of tryptophan
CC       metabolism.
CC   -!- Specific for tryptophan as substrate, but is far more active with
CC       L-tryptophan than with D-tryptophan.
CC   -!- Formerly EC 1.11.1.4 and EC 1.13.1.12.
DR   Q7SY53, T23OL_DANRE;  Q2KIQ5, T23O_BOVIN ;  Q09474, T23O_CAEEL ;
DR   Q55DB4, T23O_DICDI ;  P20351, T23O_DROME ;  P48775, T23O_HUMAN ;
DR   P48776, T23O_MOUSE ;  P21643, T23O_RAT   ;  Q5U4U6, T23O_XENLA ;
DR   Q5EBG2, T23O_XENTR ;
//