ID 1.13.11.45 DE Linoleate 11-lipoxygenase. AN Linoleate dioxygenase. AN Manganese lipoxygenase. CA Linoleate + O(2) = (9Z,12Z)-(11S)-11-hydroperoxyoctadeca-9,12-dienoate. CC -!- The product (9Z,12Z)-(11S)-11-hydroperoxyoctadeca-9,12-dienoate, CC is converted, more slowly, into (9Z,11E)-(13R)-13- CC hydroperoxyoctadeca-9,11-dienoate. CC -!- The enzyme from the fungus Gaeumannomyces graminis requires Mn(2+). CC -!- It also acts on alpha-linolenate, whereas gamma-linolenate is a poor CC substrate. CC -!- Oleate and arachidonate are not substrates. //