| Official Name |
|---|
| 9-cis-epoxycarotenoid dioxygenase.
|
| Alternative Name(s) |
|---|
| NCED. |
| Nine-cis-epoxycarotenoid dioxygenase. |
| VP14. |
| Reaction catalysed |
|---|
- A 9-cis-epoxycarotenoid + O(2) <=> 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal
- 9-cis-violaxanthin + O(2) <=> 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al
- 9'-cis-neoxanthin + O(2) <=> 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al
|
| Cofactor(s) |
|---|
| Iron.
|
| Comment(s) |
|---|
- Acts on 9-cis-violaxanthin and 9'-cis-neoxanthin but not on the all-
trans isomers.
- In vitro, it will cleave 9-cis-zeaxanthin.
- Catalyzes the first step of abscisic-acid biosynthesis from
carotenoids in chloroplasts, in response to water stress.
- The other enzymes involved in the abscisic-acid biosynthesis pathway
are EC 1.1.1.288, EC 1.2.3.14 and EC 1.14.13.93.
|
| Cross-references |
|---|
| BRENDA | 1.13.11.51 |
| PUMA2 | 1.13.11.51 |
| PRIAM enzyme-specific profiles | 1.13.11.51 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.13.11.51 |
| IUBMB Enzyme Nomenclature | 1.13.11.51 |
| IntEnz | 1.13.11.51 |
| MEDLINE | Find literature relating to 1.13.11.51 |
| MetaCyc | 1.13.11.51 |
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