ID   1.14.12.18
DE   Biphenyl 2,3-dioxygenase.
AN   Biphenyl dioxygenase.
CA   Biphenyl + NADH + O(2) = (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol +
CA   NAD(+).
CF   Iron.
CC   -!- The enzyme from Burkholderia fungorum strain LB400 (previously
CC       Pseudomonas sp.) is part of a multicomponent system composed of an
CC       NADH:ferredoxin oxidoreductase (FAD cofactor), a [2Fe-2S] Rieske-type
CC       ferredoxin, and a terminal oxygenase that contains a [2Fe-2S] Rieske-
CC       type iron-sulfur cluster and a catalytic mononuclear nonheme iron
CC       center.
CC   -!- Chlorine-substituted biphenyls can also act as substrates.
CC   -!- Similar to the three-component enzyme systems EC 1.14.12.3 and
CC       EC 1.14.12.11.
PR   PROSITE; PDOC00493;
DR   Q52438, BPHA1_PSES1;  Q52439, BPHA2_PSES1;  P37333, BPHA_BURXL ;
DR   Q46372, BPHA_COMTE ;  Q52028, BPHA_PSEPS ;  P37334, BPHE_BURXL ;
DR   Q46373, BPHE_COMTE ;
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