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NiceZyme View of ENZYME: EC 1.14.13.41

Official Name
Tyrosine N-monooxygenase.
Alternative Name(s)
CYP79A1.
Tyrosine N-hydroxylase.
Reaction catalysed
L-tyrosine + O(2) + NADPH <=> N-hydroxy-L-tyrosine + NADP(+) + H(2)O N-hydroxy-L-tyrosine + O(2) + NADPH <=> N,N-dihydroxy-L-tyrosine + NADP(+) + H(2)O N,N-dihydroxy-L-tyrosine <=> (Z)-(4-hydroxyphenylacetaldehyde oxime) + CO(2) + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
Involved in the biosynthesis of the cyanogenic glucoside dhurrin in sorghum, along with EC 1.14.13.68 and EC 2.4.1.85. Some 2-(4-hydroxyphenyl)-1-nitroethane is formed as a side product.
Cross-references
PROSITE	PDOC00081
BRENDA	1.14.13.41
PUMA2	1.14.13.41
PRIAM enzyme-specific profiles	1.14.13.41
KEGG Ligand Database for Enzyme Nomenclature	1.14.13.41
IUBMB Enzyme Nomenclature	1.14.13.41
IntEnz	1.14.13.41
MEDLINE	Find literature relating to 1.14.13.41
MetaCyc	1.14.13.41

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