ID   1.14.13.70
DE   Sterol 14-demethylase.
AN   Cytochrome P450 51.
AN   Lanosterol 14-alpha-demethylase.
AN   Lanosterol 14-demethylase.
AN   Obtusufoliol 14-demethylase.
AN   Sterol 14-alpha-demethylase.
CA   Obtusifoliol + 3 O(2) + 3 NADPH = 4-alpha-methyl-5-alpha-ergosta-
CA   8,14,24(28)-trien-3-beta-ol + formate + 3 NADP(+) + 4 H(2)O.
CF   Heme-thiolate.
CC   -!- The enzyme (P450) catalyzes successive hydroxylations of the
CC       14-alpha-methyl group and C-15, followed by elimination as formate
CC       leaving the 14(15) double bond.
CC   -!- This enzyme acts on a range of steroids with a 14-alpha-methyl group.
PR   PROSITE; PDOC00081;
DR   Q4PJW3, CP51A_BOVIN;  Q16850, CP51A_HUMAN;  O46420, CP51A_PIG  ;
DR   Q5RE72, CP51A_PONAB;  Q64654, CP51A_RAT  ;  Q759W0, CP51_ASHGO ;
DR   P10613, CP51_CANAL ;  P50859, CP51_CANGA ;  P14263, CP51_CANTR ;
DR   Q9UVC3, CP51_CUNEL ;  Q1ZXH9, CP51_DICDI ;  Q02315, CP51_ISSOR ;
DR   Q5UQI3, CP51_MIMIV ;  P0A513, CP51_MYCBO ;  P0A512, CP51_MYCTU ;
DR   Q5IZM4, CP51_MYCVP ;  Q12664, CP51_PENIT ;  Q09736, CP51_SCHPO ;
DR   P93846, CP51_SORBI ;  O14442, CP51_UNCNE ;  P49602, CP51_USTMA ;
DR   P93596, CP51_WHEAT ;  P10614, CP51_YEAST ;
//