ID   1.14.13.79
DE   Ent-kaurenoic acid oxidase.
CA   (1) Ent-kaur-16-en-19-oate + NADPH + O(2) = ent-7-alpha-hydroxykaur-16-
CA   en-19-oate + NADP(+) + H(2)O.
CA   (2) Ent-7-alpha-hydroxykaur-16-en-19-oate + NADPH + O(2) = gibberellin
CA   A(12) aldehyde + NADP(+) + 2 H(2)O.
CA   (3) Gibberellin A(12) aldehyde + NADPH + O(2) = gibberellin A(12) +
CA   NADP(+) + H(2)O.
CC   -!- Requires cytochrome P450.
CC   -!- Catalyzes three sucessive oxidations of ent-kaurenoic acid.
CC   -!- The second step includes a ring-B contraction giving the gibbane
CC       skeleton.
CC   -!- In Cucurbita maxima, ent-6-alpha,7-alpha-dihydroxykaur-16-en-19-oate
CC       is also formed.
PR   PROSITE; PDOC00081;
DR   O23051, KAO1_ARATH ;  Q9AXH9, KAO1_HORVU ;  Q9C5Y2, KAO2_ARATH ;
//