ID   1.2.1.27
DE   Methylmalonate-semialdehyde dehydrogenase (acylating).
AN   MMSA dehydrogenase.
AN   MSDH.
CA   2-methyl-3-oxopropanoate + CoA + H(2)O + NAD(+) = propanoyl-CoA +
CA   HCO(3)(-) + NADH.
CC   -!- Also converts 3-oxopropanoate into acetyl-CoA.
CC   -!- The reaction occurs in two steps with the decarboxylation process
CC       preceding CoA-binding.
CC   -!- Bicarbonate rather than CO(2) is released as a final product.
PR   PROSITE; PDOC00068;
DR   A0RDW1, IOLA1_BACAH;  Q81QR5, IOLA1_BACAN;  Q63BL0, IOLA1_BACCZ;
DR   Q6HJ19, IOLA1_BACHK;  Q65IX1, IOLA1_BACLD;  Q5WKZ1, IOLA1_BACSK;
DR   A9VF06, IOLA1_BACWK;  Q5L025, IOLA1_GEOKA;  A4IPB2, IOLA1_GEOTN;
DR   Q8ES27, IOLA1_OCEIH;  A0REB5, IOLA2_BACAH;  Q81QB6, IOLA2_BACAN;
DR   Q63B74, IOLA2_BACCZ;  Q6HIK3, IOLA2_BACHK;  Q65D00, IOLA2_BACLD;
DR   Q5WH11, IOLA2_BACSK;  A9VMS6, IOLA2_BACWK;  Q5KYR4, IOLA2_GEOKA;
DR   A4IPF5, IOLA2_GEOTN;  Q8EMV4, IOLA2_OCEIH;  Q4V1F6, IOLA3_BACCZ;
DR   Q5KYK0, IOLA3_GEOKA;  A7ZAI1, IOLA_BACA2 ;  Q738L2, IOLA_BACC1 ;
DR   A7GPH3, IOLA_BACCN ;  Q81DR5, IOLA_BACCR ;  Q9KAH5, IOLA_BACHD ;
DR   A7BJC4, IOLA_BACNA ;  A8FDV4, IOLA_BACP2 ;  P42412, IOLA_BACSU ;
DR   A5YBJ3, IOLA_LACCA ;  Q92EQ7, IOLA_LISIN ;  Q723T1, IOLA_LISMF ;
DR   Q8Y9Y4, IOLA_LISMO ;  Q17M80, MMSA_AEDAE ;  Q7QC84, MMSA_ANOGA ;
DR   Q0WM29, MMSA_ARATH ;  Q07536, MMSA_BOVIN ;  P52713, MMSA_CAEEL ;
DR   Q54I10, MMSA_DICDI ;  Q7KW39, MMSA_DROME ;  Q29HB2, MMSA_DROPS ;
DR   Q02252, MMSA_HUMAN ;  Q9EQ20, MMSA_MOUSE ;  P28810, MMSA_PSEAE ;
DR   Q02253, MMSA_RAT   ;
//