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NiceZyme View of ENZYME: EC 1.3.1.48

Official Name
15-oxoprostaglandin 13-oxidase.
Alternative Name(s)
15-oxo-Delta(13)-prostaglandin reductase.
Prostaglandin 13-reductase.
Reaction catalysed
11-alpha-hydroxy-9,15-dioxoprost-5-enoate + NAD(P)(+) <=> (5Z)-(13E)-11-alpha-hydroxy-9,15-dioxoprosta-5,13-dienoate + NAD(P)H
Comment(s)
  • Reduces 15-oxoprostaglandins to 13,14-dihydro derivatives.
  • The enzyme from placenta is specific for NAD(+).
Cross-references
BRENDA1.3.1.48
PUMA21.3.1.48
PRIAM enzyme-specific profiles1.3.1.48
KEGG Ligand Database for Enzyme Nomenclature1.3.1.48
IUBMB Enzyme Nomenclature1.3.1.48
IntEnz1.3.1.48
MEDLINEFind literature relating to 1.3.1.48
MetaCyc1.3.1.48
UniProtKB/Swiss-Prot
Q3SZJ4, LTB4D_BOVIN;  Q9EQZ5, LTB4D_CAVPO;  Q14914, LTB4D_HUMAN;  
Q91YR9, LTB4D_MOUSE;  Q29073, LTB4D_PIG;  Q28719, LTB4D_RABIT;  
P97584, LTB4D_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
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