ID   1.3.2.3
DE   L-galactonolactone dehydrogenase.
AN   Galactonolactone dehydrogenase.
AN   GLDase.
AN   GLDHase.
AN   L-galactono-gamma-lactone dehydrogenase.
CA   (1) L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate +
CA   2 ferrocytochrome c + 2 H(+).
CA   (2) L-ascorbate + 2 ferricytochrome c = L-dehydroascorbate +
CA   2 ferrocytochrome c + 2 H(+).
CC   -!- Catalyzes the final step in the biosynthesis of L-ascorbic acid in
CC       higher plants and in nearly all higher animals with the exception of
CC       primates and some birds.
CC   -!- Very specific for its substrate L-galactono-1,4-lactone as
CC       D-galactono-gamma-lactone, D-gulono-gamma-lactone, L-gulono-gamma-
CC       lactone, D-erythronic-gamma-lactone, D-xylonic-gamma-lactone,
CC       L-mannono-gamma-lactone, D-galactonate, D-glucuronate and D-gluconate
CC       are not substrates.
CC   -!- FAD, NAD(+), NADP(+) and O(2) (cf. EC 1.3.3.12) cannot act as
CC       electron acceptor.
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