ID   1.5.1.28
DE   Opine dehydrogenase.
CA   (2S)-2-((1-(R)-carboxyethyl)amino)pentanoate + NAD(+) + H(2)O = L-2-
CA   aminopentanoic acid + pyruvate + NADH.
CC   -!- In the forward direction, the enzyme from Arthrobacter sp. acts also
CC       on secondary amine dicarboxylates such as
CC       N-(1-carboxyethyl)methionine and N-(1-carboxyethyl)phenylalanine.
CC   -!- Dehydrogenation forms an imine, which dissociates to the amino acid
CC       and pyruvate.
CC   -!- In the reverse direction, the enzyme acts also on neutral amino acids
CC       as an amino donor.
CC   -!- They include L-amino acids such as 2-aminopentanoic acid,
CC       2-aminobutyric acid, 2-aminohexanoic acid, 3-chloroalanine,
CC       O-acetylserine, methionine, isoleucine, valine, phenylalanine,
CC       leucine and alanine.
CC   -!- The amino acceptors include 2-oxoacids such as pyruvate,
CC       oxaloacetate, glyoxylate and 2-oxobutyrate.
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