| Official Name |
|---|
| Prenylcysteine oxidase.
|
| Alternative Name(s) |
|---|
| Prenylcysteine lyase. |
| Reaction catalysed |
|---|
| An S-prenyl-L-cysteine + O(2) + H(2)O <=> a prenal + L-cysteine + H(2)O(2) |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- Cleaves the thioether bond of S-prenyl-L-cysteines, such as
S-farnesylcysteine and S-geranylgeranylcysteine.
- N-acetyl-prenylcysteine and prenylcysteinyl peptides are not
substrates.
- May represent the final step in the degradation of prenylated
proteins in mammalian tissues.
- Originally thought to be a simple lyase, EC 4.4.1.18.
|
| Cross-references |
|---|
| BRENDA | 1.8.3.5 |
| PUMA2 | 1.8.3.5 |
| PRIAM enzyme-specific profiles | 1.8.3.5 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.8.3.5 |
| IUBMB Enzyme Nomenclature | 1.8.3.5 |
| IntEnz | 1.8.3.5 |
| MEDLINE | Find literature relating to 1.8.3.5 |
| MetaCyc | 1.8.3.5 |
| UniProtKB/Swiss-Prot |
|
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