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ENZYME

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NiceZyme View of ENZYME: EC 2.3.1.109

Official Name

Arginine N-succinyltransferase.

Alternative Name(s)

AOST.

Arginine and ornithine N(2)-succinyltransferase.

Arginine succinyltransferase.

AST.

Reaction catalysed

Succinyl-CoA + L-arginine <=> CoA + N(2)-succinyl-L-arginine

Comment(s)

Also acts on L-ornithine.
This is the first enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.81, EC 1.2.1.71 and EC 3.5.1.96.

Cross-references

BRENDA

PUMA2

PRIAM enzyme-specific profiles

KEGG Ligand Database for Enzyme Nomenclature

IUBMB Enzyme Nomenclature

IntEnz

MEDLINE

MetaCyc