| Official Name |
|---|
| FAD synthetase.
|
| Alternative Name(s) |
|---|
| FAD diphosphorylase. |
| FAD pyrophosphorylase. |
| FADS. |
| Flavin adenine dinucleotide synthetase. |
| FMN adenylyltransferase. |
| Reaction catalysed |
|---|
| ATP + FMN <=> diphosphate + FAD |
| Cofactor(s) |
|---|
| Magnesium.
|
| Comment(s) |
|---|
- Highly specific for ATP as phosphate donor.
- The cofactors FMN and FAD participate in numerous processes in all
organisms, including mitochondrial electron transport,
photosynthesis, fatty-acid oxidation, and metabolism of vitamin B6,
vitamin B12 and folates.
- While monofunctional FAD synthetase is found in eukaryotes and in
some prokaryotes, most prokaryotes have a bifunctional enzyme that
exhibits both this activity and that of EC 2.7.1.26.
|
| Cross-references |
|---|
| BRENDA | 2.7.7.2 |
| PUMA2 | 2.7.7.2 |
| PRIAM enzyme-specific profiles | 2.7.7.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.7.2 |
| IUBMB Enzyme Nomenclature | 2.7.7.2 |
| IntEnz | 2.7.7.2 |
| MEDLINE | Find literature relating to 2.7.7.2 |
| MetaCyc | 2.7.7.2 |
| UniProtKB/Swiss-Prot |
| Q68EH8, FAD1_DANRE; | Q8NFF5, FAD1_HUMAN; | Q8R123, FAD1_MOUSE; |
| Q5RCH4, FAD1_PONAB; | O74841, FAD1_SCHPO; | P38913, FAD1_YEAST; |
| Q626I0, FLAD1_CAEBR; | Q22017, FLAD1_CAEEL; | Q6ING7, FLAD1_XENLA; |
| Q7NBZ0, MNMA_MYCGA; | P54575, RIBC_BACSU; | P57250, RIBF_BUCAI; |
| Q8K9Z1, RIBF_BUCAP; | Q59263, RIBF_CORAM; | P0AG42, RIBF_ECO57; |
| P0AG41, RIBF_ECOL6; | P0AG40, RIBF_ECOLI; | P44957, RIBF_HAEIN; |
| P47391, RIBF_MYCGE; | P75587, RIBF_MYCPN; | P22990, RIBF_PSEFL; |
| O84990, RIBF_RHOOP; | P0AG43, RIBF_SHIFL; | P73651, RIBF_SYNY3; |
|
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