PROSITE - Entry: PS00075

ExPASy Home page

Site Map

Search ExPASy

Contact us

PROSITE

Hosted by

Mirror sites:

The ExPASy Server requires Javascript to be fully functional. You may not see all the information available for this page (More information).

Entry: PS00075

General information about the entry
Entry name	DHFR_1
Accession number	PS00075
Entry type	PATTERN
Date	APR-1990 (CREATED); NOV-1997 (DATA UPDATE); OCT-2008 (INFO UPDATE).
PROSITE Documentation	PDOC00072
Name and characterization of the entry
Description	Dihydrofolate reductase (DHFR) domain signature.
Pattern	[LVAGC]-[LIF]-G-x(4)-[LIVMF]-P-W-x(4,5)-[DE]-x(3)-[FYIV]-x(3)-[STIQ].
Numerical results
UniProtKB/Swiss-Prot release number: 56.4, total number of sequence entries in that release: 400771. Total number of hits in UniProtKB/Swiss-Prot: 89 hits in 89 different sequences Number of hits on proteins that are known to belong to the set under consideration: 87 hits in 87 different sequences Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences Number of false hits (on unrelated proteins): 2 hits in 2 different sequences Number of known missed hits: 6 Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
Comments
VERSION: 1
Cross-references
UniProtKB/Swiss-Prot	True positive hits: DRTS1_ARATH (Q05762), DRTS2_ARATH (Q05763), DRTS_DAUCA (P45350), DRTS_LEIAM (P16126), DRTS_LEIMA (P07382), DRTS_MAIZE (O81395), DRTS_ORYSJ (Q2QRX6), DRTS_PARTE (Q27828), DRTS_PLABA (Q27713), DRTS_PLACH (P20712), DRTS_PLAFK (P13922), DRTS_PLAVI (O02604), DRTS_PLAVN (P46103), DRTS_SOYBN (P51820), DRTS_TOXGO (Q07422), DRTS_TRYBB (Q27783), DRTS_TRYCR (Q27793), DYR10_ECOLX (Q04515), DYR13_ECOLX (Q59408), DYR15_ECOLX (P78218), DYR1_ECOLX (P00382), DYR1_HALMA (Q5V3R2), DYR2_HALMA (Q5V600), DYR3_SALTY (P12833), DYR5_ECOLX (P11731), DYR6_PROMI (P95524), DYR7_ECOLX (P27422), DYR8_ECOLX (P0ABQ7), DYR8_SHISO (P0ABQ8), DYR9_ECOLX (Q59397), DYRA_STAAU (P13955), DYR_AEDAL (P28019), DYR_BACSU (P11045), DYR_BOVIN (P00376), DYR_BPT4 (P04382), DYR_BUCAI (P57243), DYR_BUCAP (Q8K9Z8), DYR_BUCBP (Q89AV2), DYR_CAEEL (Q93341), DYR_CANAL (P22906), DYR_CHICK (P00378), DYR_CITFR (P31073), DYR_CRYNE (Q07801), DYR_DROME (P17719), DYR_ECOL6 (P0ABQ5), DYR_ECOLI (P0ABQ4), DYR_ENTAE (P31074), DYR_ENTFC (P00380), DYR_HAEIN (P43791), DYR_HALVO (P15093), DYR_HELVI (Q9U8B8), DYR_HUMAN (P00374), DYR_KLEAE (P27498), DYR_LACCA (P00381), DYR_LACLA (Q59487), DYR_MESAU (P04753), DYR_MOUSE (P00375), DYR_MYCBO (P0A547), DYR_MYCGE (P47470), DYR_MYCLE (Q9CBW1), DYR_MYCPN (P78028), DYR_MYCPU (Q98Q32), DYR_MYCTU (P0A546), DYR_NEIGO (P04174), DYR_NEIMA (Q9JSQ9), DYR_NEIMB (Q9K168), DYR_PIG (P00377), DYR_PNECA (P16184), DYR_RAT (Q920D2), DYR_SCHPO (P36591), DYR_SHIFL (P0ABQ6), DYR_SHV21 (P09503), DYR_SHV24 (P27421), DYR_SHV2C (P22573), DYR_STAAC (Q5HFZ7), DYR_STAAM (P0A016), DYR_STAAN (P99079), DYR_STAAR (Q6GGY1), DYR_STAAS (Q6G9D5), DYR_STAAU (P0A017), DYR_STAAW (Q8NWQ9), DYR_STAEP (P0C0P0), DYR_STAEQ (Q5HPB1), DYR_STAES (P0C0P1), DYR_STAHA (Q54277), DYR_STRPN (Q54801), DYR_YEAST (P07807) False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile): DRTS_CRIFA (Q23695), DRTS_MIMIV (Q5UQG3), DYRL1_HUMAN (Q86XF0), DYR_ENCCU (O62583), DYR_THEMA (Q60034), DYR_UREPA (Q9PR30) False positive hits (sequences which do not belong to the set under consideration): Y2900_MYCTU (P65408), Y2924_MYCBO (P65409) Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
PDB [Detailed view]	1AI9; 1AO8; 1AOE; 1BOZ; 1BZF; 1CD2; 1DAJ; 1DDR; 1DDS; 1DF7; 1DG5; 1DG7; 1DG8; 1DHF; 1DIS; 1DIU; 1DLR; 1DR1; 1DR2; 1DR3; 1DR4; 1DR5; 1DR6; 1DR7; 1DRA; 1DRE; 1DRF; 1DRH; 1DYH; 1DYI; 1DYJ; 1DYR; 1E26; 1HFP; 1HFQ; 1HFR; 1IA1; 1IA2; 1IA3; 1IA4; 1J3I; 1J3J; 1J3K; 1JOL; 1JOM; 1JUV; 1KLK; 1KMS; 1KMV; 1LUD; 1LY3; 1LY4; 1M78; 1M79; 1M7A; 1MVS; 1MVT; 1OHJ; 1OHK; 1PD8; 1PD9; 1PDB; 1RA1; 1RA2; 1RA3; 1RA8; 1RA9; 1RB2; 1RB3; 1RC4; 1RD7; 1RE7; 1RF7; 1RG7; 1RH3; 1RX1; 1RX2; 1RX3; 1RX4; 1RX5; 1RX6; 1RX7; 1RX8; 1RX9; 1S3U; 1S3V; 1S3W; 1S3Y; 1TDR; 1U72; 1VDR; 1VJ3; 1YHO; 2ANO; 2ANQ; 2BL9; 2BLA; 2BLB; 2BLC; 2C2S; 2C2T; 2CD2; 2CIG; 2D0K; 2DHF; 2FZH; 2FZI; 2FZJ; 2H2Q; 2HM9; 2HQP; 2INQ; 3CD2; 3DFR; 3DRC; 4CD2; 4DFR; 7DFR; 8DFR;

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission

If you would like to retrieve all the Swiss-Prot entries referenced in the DR lines of this entry (with the exception of false positive hits) , you can enter a file name. These entries will then be saved to a file under this name. (Please note that this temporary file will only be kept for 1 week.)