Species code:	CHLTR
Taxonomy:	Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydia (TaxID: 813) [NEWT/ NCBI]
Description:	Chlamydia trachomatis infection is an important cause of preventable blindness and sexually transmitted disease (STD) in humans. There are 15 serovariants that exhibit distinct organotropism for the eye or the urogenital tract and are separated according to the pathobiotypes. Trachoma biovariants consist of serovars A, B, Ba, C, D, E, F, G, H, I, J and K. LGV (Lymphogranuloma venereum) biovariants consist of serovars L1, L2 and L3. Trachoma biovariants are noninvasive and epitheliotropic strains that cause blinding trachoma (A to C) or sexually transmitted diseases. LGV biovariants cause sexually transmitted diseases with disseminating infection of draining regional lymph nodes. The trpBA operon encoding tryptophan synthase is functional in STD serovars, whereas trpBA harbors mutations that inactivate the enzyme in ocular serovars. Chlamydia trachomatis is an obligate intracellular parasite depending on the host machinery for ATP synthesis. Chlamydial life cycle comprehends an intracellular metabolically- active "reticular body" and an inert extracellular spore-like "elementary body" equipped with a unique disulfide-cross-linked protein envelope. Chlamydia trachomatis (strain D/UW-3) is a genitotropic isolate.
Properties:	Presence of flagella: No Interaction: Animal pathogen in Mammalia (intracellular obligate) Number of membranes: 2 Number of inteins:0
Statistics:	Number of CHLTR entries in the UniProt Knowledgebase: 895 (405 in UniProtKB/Swiss-Prot + 490 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number AE001273 (circular; 1,042,519 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] MEDLINE=99000809; PubMed=9784136; [ NCBI , EBI , Israel , Japan ] Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. ; "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis."; Science 282:754-759(1998).
Web links:	CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Chlamydia&GLspecies=trachomatis&GLstrain=DUW_3CX Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid272561%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Ctra_DUW3CX Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Chlamydia_trachomatis.html NMPDR: http://www.nmpdr.org/FIG/seedviewer.cgi?pattern=272561.1;page=SearchResult PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p45_Chl_trach TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=ntct01  EBI Proteome Analysis page

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