Species code:	HELPJ
Taxonomy:	Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter (TaxID: 85963) [NEWT/ NCBI]
Description:	Micro-aerophilic, Gram-negative, slow-growing, spiral-shaped and flagellated organism. H.pylori is probably the most common cause of chronic bacterial infection of humans, present in almost half of the world population. The presence of the bacterium in the gastric mucosa is associated with chronic active gastritis and is implicated in more severe gastric diseases, including chronic atrophic gastritis, peptic ulceration and mucosa-associated lymphoid tissue lymphomas. Strain J99 was isolated in the USA in 1994 from a patient with a duodenal ulcer.
Properties:	Presence of flagella: Yes Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of HELPJ entries in the UniProt Knowledgebase: 1488 (564 in UniProtKB/Swiss-Prot + 924 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number AE001439 (circular; 1,643,831 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] MEDLINE=99120557; PubMed=9923682; [ NCBI , EBI , Israel , Japan ] Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C., Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J., Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D., Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J. ; "Genomic sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori."; Nature 397:176-180(1999).
Web links:	CampyDB: http://xbase.bham.ac.uk/campydb/genome.pl?id=1108 CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Helicobacter&GLspecies=pylori&GLstrain=J99 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid85963%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Hpyl_J99 Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Helicobacter_pylori.html PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p234_Hel_pylor PyloriGene: http://genolist.pasteur.fr/PyloriGene/genome.cgi TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=nthp01  EBI Proteome Analysis page

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