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UniProtKB/Swiss-Prot entry A1K7M2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRD_AZOSB
Primary accession number A1K7M2
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on February 6, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 17)
Name and origin of the protein
Protein name Dihydroorotate dehydrogenase
Synonyms EC 1.3.3.1
Dihydroorotate oxidase
DHOdehase
DHODase
DHOD
Gene name
Name: pyrD
OrderedLocusNames: azo2210
From
Azoarcus sp. (strain BH72) [TaxID: 62928] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales; Rhodocyclaceae; Azoarcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nbt1243; PubMed=17057704 [NCBI, ExPASy, EBI, Israel, Japan]
Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J., Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C., Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J., Weidner S., Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.;
"Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72.";
Nat. Biotechnol. 24:1385-1391(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AM406670; CAL94827.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_933714.1; -.
3D structure databases
ModBase A1K7M2.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from HAMAP).
GO:0004158; Molecular function: dihydroorotate oxidase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00225; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR012135; DHO_DHase_1_2.
IPR005719; DHO_DHase_2.
IPR001295; Dihydroorotate_DHase_core.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF01180; DHO_dh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000164; DHO_oxidase; 1.
TIGRFAMs TIGR01036; pyrD_sub2; 1.
PROSITE PS00911; DHODEHASE_1; 1.
PS00912; DHODEHASE_2; 1.
BLOCKS A1K7M2.
Genome annotation databases
GeneID 4608363; -.
GenomeReviews AM406670_GR; azo2210.
KEGG azo:azo2210; -.
CMR A1K7M2; azo2210.
Other
ProtoNet A1K7M2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; Flavoprotein; FMN; Membrane; Oxidoreductase; Pyrimidine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   338  338     Dihydroorotate dehydrogenase. PRO_1000024152
ACT_SITE   172   172        Nucleophile (By similarity). 
Sequence information
Length: 338 AA [This is the length of the unprocessed precursor] Molecular weight: 36234 Da [This is the MW of the unprocessed precursor] CRC64: B3028C831DC3CA8B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLYDIARPFL FSLDAETAHE FTLAALNLAG RTLPAGKPEA ADAVRVMGID FPNRIGLAAG 

        70         80         90        100        110        120 
LDKNGEAIDG LARLGFGFIE IGTITPRPQP GNPRPRLFRL PEVRGIINRM GFNNHGVDTL 

       130        140        150        160        170        180 
VANVKAARFK GVLGINIGKN FDTPIENAAD DYLACLDKVY PLASYVTVNI SSPNTKNLRQ 

       190        200        210        220        230        240 
LQGESELDDL LGRLKSAQQR LADQHGRYVP LTLKIAPDLE AAQITNIADA LRRHRIDAVI 

       250        260        270        280        290        300 
ATNTTISRDK VQGVRFAEQQ GGLSGAPVFE ASTAVVAQLA TALGGELPII AAGGVMDTRS 

       310        320        330 
ARAKLEAGAS LVQLYSGLIY RGPCLVRECV RATADFPR
A1K7M2 in FASTA format

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