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UniProtKB/Swiss-Prot entry A2BLC6

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P_HYPBU
Primary accession number A2BLC6
Secondary accession numbers None
Integrated into Swiss-Prot on September 11, 2007
Sequence was last modified on February 20, 2007 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 16)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase
Synonyms GAPDH
EC 1.2.1.59
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene name
Name: gap
OrderedLocusNames: Hbut_0939
From
Hyperthermus butylicus (strain DSM 5456 / JCM 9403) [TaxID: 415426] [HAMAP proteome]
Taxonomy Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; Pyrodictiaceae; Hyperthermus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=17350933 [NCBI, ExPASy, EBI, Israel, Japan]
Bruegger K., Chen L., Stark M., Zibat A., Redder P., Ruepp A., Awayez M., She Q., Garrett R.A., Klenk H.-P.;
"The genome of Hyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C.";
Archaea 2:127-135(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000493; ABM80787.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001013132.1; -.
3D structure databases
ModBase A2BLC6.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004365; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00559; -; 1.
PBIL [Tree]
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006436; Glyceraldehyde-3-P_DHase_2_arc.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
ProDom PD007761; GAPDH_like; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01546; GAPDH-II_archae; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS A2BLC6.
Genome annotation databases
GeneID 4782951; -.
GenomeReviews CP000493_GR; Hbut_0939.
KEGG hbu:Hbut_0939; -.
CMR A2BLC6; Hbut_0939.
Other
ProtoNet A2BLC6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   343  343     Glyceraldehyde-3-phosphate dehydrogenase. PRO_0000300970
NP_BIND   13    14  2     NAD (By similarity). 
REGION   140   142  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   195   196  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   141   141        Nucleophile (By similarity). 
BINDING   111   111        NAD; via amide nitrogen (By similarity). 
BINDING   169   169        NAD (By similarity). 
BINDING   302   302        NAD; via carbonyl oxygen (By similarity). 
Sequence information
Length: 343 AA [This is the length of the unprocessed precursor] Molecular weight: 37560 Da [This is the MW of the unprocessed precursor] CRC64: DFAFF32D589DCBFF [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MARVRVGVNG FGTIGKRVAE AIMLQPDMEL VGVTKTKPDY TAKYAVSRGI PVYVPKESLE 

        70         80         90        100        110        120 
EFQAKGIEPA GTIEELLEKV DVIVDATPGG TGRKYKPLYE KAGVKMIFQG GEKADIAELS 

       130        140        150        160        170        180 
FSTLCNYEQA LGKTSLRVVS CNTTGLLRAI CSISRLAPVR RVRATIVRRA ADPKEIKRGP 

       190        200        210        220        230        240 
VNAIKPDPVK TPSHHALDVK TVLPDLDIVT MAVVVPTTLM HVHIVYAELE KPVTREDVVA 

       250        260        270        280        290        300 
TFESTPRILL ADASYGLAST AELVEYARDL GRKRYDIPEL IVWLDSIAVN GVEVMWMQAV 

       310        320        330        340 
HQEAIVVPEN IDAIRAVAEL AKTAEETIRI TDERLGLLKG RIP
A2BLC6 in FASTA format

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