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UniProtKB/Swiss-Prot entry A2RL29

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUAC_LACLM
Primary accession number A2RL29
Secondary accession numbers None
Integrated into Swiss-Prot on June 26, 2007
Sequence was last modified on March 6, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 13)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: llmg_1412
From
Lactococcus lactis subsp. cremoris (strain MG1363) [TaxID: 416870] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Lactococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.01768-06; PubMed=17307855 [NCBI, ExPASy, EBI, Israel, Japan]
Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J.;
"The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363.";
J. Bacteriol. 189:3256-3270(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AM406671; CAL97995.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001032707.1; -.
3D structure databases
SMR A2RL29; 4-324.
ModBase A2RL29.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
BLOCKS A2RL29.
Genome annotation databases
GeneID 4798556; -.
GenomeReviews AM406671_GR; llmg_1412.
KEGG llm:llmg_1412; -.
CMR A2RL29; llmg_1412.
Other
ProtoNet A2RL29.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   329  329     GMP reductase. PRO_0000292054
NP_BIND   207   230  24     NADP (Potential). 
ACT_SITE   178   178        Thioimidate intermediate (By similarity). 
Sequence information
Length: 329 AA [This is the length of the unprocessed precursor] Molecular weight: 35814 Da [This is the MW of the unprocessed precursor] CRC64: 07C0D063EC4D8F02 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNNLNSVFDY EDIQLIPNKC VINSRSEADT SVKLGNYTFK LPVVPANMQT IIDDKIAEML 

        70         80         90        100        110        120 
AKEGYFYIMH RFEAENRAAF IKKMHKDGLI ASISVGVKAD EHAFIREISA EALIPEFITI 

       130        140        150        160        170        180 
DIAHGHADSV IKTIQLIKRL MPQTFVIAGN VGTPEAVREL ENAGADATKV GIGPGKVCIT 

       190        200        210        220        230        240 
KVKTGFGTGG WQLAAVKWCA KAASKPVIAD GGIRTHGDVA KSIRMGATMV MVGSLFAAHE 

       250        260        270        280        290        300 
ESPGQTVERD GQLFKEYFGS ASEYQKGEHK NVEGKKILLP HKGSLKDTLK EMEEDLQSSI 

       310        320 
SYAGGRDLSA LTKVDYVVVK NSIWNGDAI
A2RL29 in FASTA format

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