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UniProtKB/Swiss-Prot entry A3N3D8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSI_ACTP2
Primary accession number A3N3D8
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on April 3, 2007 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 13)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: APL_1842
From
Actinobacillus pleuropneumoniae serotype 5b (strain L20) [TaxID: 416269] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Actinobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.01845-07; PubMed=18065534 [NCBI, ExPASy, EBI, Israel, Japan]
Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M., Nash J.H.E.;
"The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b).";
J. Bacteriol. 190:1495-1496(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000569; ABN74924.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001054529.1; -.
3D structure databases
ModBase A3N3D8.
Ontologies
GO
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; 1.
BLOCKS A3N3D8.
Genome annotation databases
GeneID 4848697; -.
GenomeReviews CP000569_GR; APL_1842.
KEGG apl:APL_1842; -.
CMR A3N3D8; APL_1842.
Other
ProtoNet A3N3D8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   588  588     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_1000068756
METAL   442   442        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   448   448        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   487   487        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   491   491        Iron (siroheme axial ligand) (By similarity). 
METAL   491   491        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 588 AA [This is the length of the unprocessed precursor] Molecular weight: 66761 Da [This is the MW of the unprocessed precursor] CRC64: 3CBA5BBE72775200 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSDKKIKGLE WQEKPLSDNE RLKTDSNFLR GTILDDLKDD LTGGFKGDNF QLIRFHGMYE 

        70         80         90        100        110        120 
QDDRDIRAER LEEKLEPLKF MLLRCRLPGG IIKPYQWIEI DKFAREHTRY QSIRLTNRQT 

       130        140        150        160        170        180 
FQYHGVPKGK LQPMHRLLHS IGLDSIATAA DMNRNVLCTS NPIESELHQQ AYEFAKKISE 

       190        200        210        220        230        240 
HLLPRSRGYL DVWVDGKKVE SSDDLLKIED EPILGKTYLP RKFKTAVAIP PLNDVDVYAN 

       250        260        270        280        290        300 
DLNFIAIQDE NGQLCGFNVL VGGGLSFEHG NTKTYPNVAY SLGFVPLEHT LAAAEGVVKT 

       310        320        330        340        350        360 
QRDFGNRSDR KNARVRYTVQ NMTLDGFRAE VERCMNIKFE PTRPYEFTER GDRIGWVKGI 

       370        380        390        400        410        420 
DNNWHLTLFI ESVRITDKPE KPLMTGVLEL AKVHKGDFRI TANQNLIVAN VAEQDKAQIE 

       430        440        450        460        470        480 
AIARQYGLIQ EISKLRENAM SCVSLPTCPL AMAEAERVLP DFISELDKVL SKHNVADESI 

       490        500        510        520        530        540 
ITRITGCPNG CGRAMLAEIG LVGKAIGRYN LHIGGDRAGL RISRLYKENI TLQEIVNEID 

       550        560        570        580 
QLVARWATER QTNEAFGDFV IRSNIIAPVV NAHIDFWDAT KIIPTTII
A3N3D8 in FASTA format

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