[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P., Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.; Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Coproporphyrinogen-III + O₂ + 2 H⁺ = protoporphyrinogen-IX + 2 CO₂ + 2 H₂O.
PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the aerobic coproporphyrinogen III oxidase family.

Copyright

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Cross-references

Sequence databases

EMBL

CP000647; ABR78189.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001336419.1; -.

3D structure databases

ModBase

A6TC68.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004109;	Molecular function: coproporphyrinogen oxidase activity (inferred from electronic annotation from HAMAP).
GO:0006779;	Biological process: porphyrin biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00333; -; 1.
PBIL [Tree]

InterPro

IPR001260; Coprogen_oxidas.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.1500.10; Coprogen_oxidas; 1.

PANTHER

PTHR10755; Coprogen_oxidas; 1.

Pfam

PF01218; Coprogen_oxidas; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000166; Coproporphyri_ox; 1.

PRINTS

PR00073; COPRGNOXDASE.

PROSITE

PS01021; COPROGEN_OXIDASE; 1.

BLOCKS

A6TC68.

Genome annotation databases

GeneID

5340949; -.

GenomeReviews

CP000647_GR; KPN78578_27280.

KEGG

kpn:KPN_02779; -.

CMR

A6TC68; KPN78578_27280.

Other

ProtoNet

A6TC68.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Oxidoreductase; Porphyrin biosynthesis.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 299`	`299`		`Coproporphyrinogen III oxidase, aerobic.`	`PRO_1000019471`

Sequence information

Length: 299 AA [This is the length of the unprocessed precursor]

Molecular weight: 34212 Da [This is the MW of the unprocessed precursor]

CRC64: A75758FBAA4CB29D [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKPDAAQVKT FLLQLQDSLC QQLSAVDGAP FIEDAWQREG GGGGRSRVLR EGRVFEQAGV 

        70         80         90        100        110        120 
NFSHVHGDAM PASATAHRPE LAGRSFEAMG VSLVVHPLNP YVPTSHANVR FFIAEKPGAD 

       130        140        150        160        170        180 
PVWWFGGGFD LTPYYGFEED AVHWHRTARD LCLPFGEEVY PRYKKWCDDY FYLKHRQEQR 

       190        200        210        220        230        240 
GIGGLFFDDL NTPDFDHCFA FMQAVGNGYA DAYLPIVERR KATPYGERER HFQLYRRGRY 

       250        260        270        280        290 
VEFNLVWDRG TLFGLQTGGR TESILMSMPP LVRWEYDYQP EPGSPEAALS EFIQVRDWL

A6TC68 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools