NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Lowry S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Vieille C., Richardson P.;
"Complete sequence of Actinobacillus succinogenes 130Z.";
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Shikimate + NADP⁺ = 3-dehydroshikimate + NADPH.
PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and PEP: step 4/7 .
SIMILARITY: Belongs to the shikimate dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000746; ABR73715.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001343650.1; -.

3D structure databases

ModBase

A6VL68.

Ontologies

GO:0004764;	Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073;	Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00222; -; 1.
PBIL [Tree]

InterPro

IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.

Pfam

PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00507; aroE; 1.

BLOCKS

A6VL68.

Genome annotation databases

GeneID

5349574; -.

GenomeReviews

CP000746_GR; Asuc_0337.

KEGG

asu:Asuc_0337; -.

CMR

A6VL68; Asuc_0337.

Other

ProtoNet

A6VL68.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 269`	`269`	`Shikimate dehydrogenase.`	`PRO_0000325095`
`NP_BIND`	`126 130`	`5`	`NADP (By similarity).`
`ACT_SITE`	`65 65`		`Proton acceptor (Potential).`

Sequence information

Length: 269 AA [This is the length of the unprocessed precursor]

Molecular weight: 29758 Da [This is the MW of the unprocessed precursor]

CRC64: B8296B93544E9C3C [This is a checksum on the sequence]

        10         20         30         40         50         60 
MDNYAVWGNP IKQSKSPQIH KIFAEQTKQC MEYKAILGDP EKFETELLRF FADGAKGCNI 

        70         80         90        100        110        120 
TAPFKERAYS LADEYSERAL TAEACNTLKR LQDGRLYADN TDGAGLVSDL ERLGWLKSKQ 

       130        140        150        160        170        180 
SLLIIGAGGA TKGVLLPLLQ AQQNITLCNR TLTKARDLAD KFAPYGNIQA MKLSEIPVQK 

       190        200        210        220        230        240 
FDLVINATSL GLQGKTVDIE PEILRLAGAV YDMQYDKGKD TPFVAWAKAL GVQNVHDGFG 

       250        260 
MLVGQAAHSF YLWRGIMPDI KPLLENDLI

A6VL68 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools