[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.; Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Oxidative deamination of D-amino acids (By similarity).
CATALYTIC ACTIVITY: A D-amino acid + H₂O + acceptor = a 2-oxo acid + NH₃ + reduced acceptor.
COFACTOR: FAD (By similarity).
PATHWAY: Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1 .
SUBUNIT: Heterodimer of a small and a large subunit (By similarity).
SIMILARITY: Belongs to the dadA oxidoreductase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000822; ABV12333.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001452769.1; -.

3D structure databases

ModBase

A8AFS0.

Ontologies

GO:0008718;	Molecular function: D-amino-acid dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006524;	Biological process: alanine catabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01202; -; 1.
PBIL [Tree]

InterPro

IPR006076; FAD-dep_OxRdtase.
Graphical view of domain structure.

Pfam

PF01266; DAO; 1.
Pfam graphical view of domain structure.

ProDom

PD000139; FAD_pyr_redox; 1.
[Domain structure / List of seq. sharing at least 1 domain]

BLOCKS

A8AFS0.

Genome annotation databases

GeneID

5583101; -.

GenomeReviews

CP000822_GR; CKO_01193.

KEGG

cko:CKO_01193; -.

CMR

A8AFS0; CKO_01193.

Other

ProtoNet

A8AFS0.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; FAD; Flavoprotein; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 432`	`432`	`D-amino acid dehydrogenase small subunit.`	`PRO_1000066088`
`NP_BIND`	`3 17`	`15`	`FAD (Potential).`

Sequence information

Length: 432 AA [This is the length of the unprocessed precursor]

Molecular weight: 47691 Da [This is the MW of the unprocessed precursor]

CRC64: 08083788AF42A7B1 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MRVVILGSGV VGVTSAWYLC QAGHDVTVID REPGPALETS AANAGQISPG YAAPWAAPGV 

        70         80         90        100        110        120 
PLKAIKWMFQ RHAPLAVRLD GTQFQLKWMW QMLRNCDTRH YMENKGRMVR LAEYSRDCLK 

       130        140        150        160        170        180 
ALRASTGIQY EGRQGGTLQL FRTAQQYENA TRDIAVLEDA GVPYQLLESS RLAEVEPALA 

       190        200        210        220        230        240 
EVAHKLTGGL RLPNDETGDC QLFTQRLAQM AEQAGVTFRF NTPVEKLLYE GEQIYGVKCG 

       250        260        270        280        290        300 
DDIIKADAYV MAFGSYSTAM LKGIVDIPVY PLKGYSLTIP VAQDDGAPVS TILDETYKIA 

       310        320        330        340        350        360 
ITRFDKRIRV GGMAEIVGFN TELLQPRRET LEMVVRDLFP RGGHVEQATF WTGLRPMTPD 

       370        380        390        400        410        420 
GTPVIGRTRF KNLWLNTGHG TLGWTMACGS GQLLSDILSG RTPAIPYDDL SVARYSPGFT 

       430 
PSRPRHLHGA HN

A8AFS0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools