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UniProtKB/Swiss-Prot entry A8G9P1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PDXA_SERP5
Primary accession number A8G9P1
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on November 13, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 9)
Name and origin of the protein
Protein name 4-hydroxythreonine-4-phosphate dehydrogenase
Synonyms EC 1.1.1.262
4-(phosphohydroxy)-L-threonine dehydrogenase
Gene name
Name: pdxA
OrderedLocusNames: Spro_0725
From
Serratia proteamaculans (strain 568) [TaxID: 399741] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Serratia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P.;
"Complete sequence of chromosome of Serratia proteamaculans 568.";
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000826; ABV39831.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001476959.1; -.
3D structure databases
ModBase A8G9P1.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0050570; Molecular function: 4-hydroxythreonine-4-phosphate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0050897; Molecular function: cobalt ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0051287; Molecular function: NAD binding (inferred from electronic annotation from InterPro).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0042823; Biological process: pyridoxal phosphate biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0008615; Biological process: pyridoxine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00536; -; 1.
PBIL [Tree]
InterPro IPR005255; PyrdxlP_synth_PdxA.
Graphical view of domain structure.
Pfam PF04166; PdxA; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00557; pdxA; 1.
ProtoNet A8G9P1.
Genome annotation databases
GeneID 5605069; -.
GenomeReviews CP000826_GR; Spro_0725.
KEGG spe:Spro_0725; -.
CMR A8G9P1; Spro_0725.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cobalt; Complete proteome; Cytoplasm; Magnesium; Metal-binding; NAD; NADP; Oxidoreductase; Pyridoxine biosynthesis; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   330  330     4-hydroxythreonine-4-phosphate dehydrogenase. PRO_1000061033
METAL   166   166        Divalent metal cation; shared with dimeric partner (By similarity). 
METAL   211   211        Divalent metal cation; shared with dimeric partner (By similarity). 
METAL   266   266        Divalent metal cation; shared with dimeric partner (By similarity). 
BINDING   136   136        Substrate (By similarity). 
BINDING   137   137        Substrate (By similarity). 
BINDING   274   274        Substrate (By similarity). 
BINDING   283   283        Substrate (By similarity). 
BINDING   292   292        Substrate (By similarity). 
Sequence information
Length: 330 AA [This is the length of the unprocessed precursor] Molecular weight: 35205 Da [This is the MW of the unprocessed precursor] CRC64: 031CDA1113DF029D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MHNNNRIVIT PGEPAGVGPD LVAALAQQDW PVELVVCADP ALLLERARQL DLPLQLRTYQ 

        70         80         90        100        110        120 
PQQPAQPQRA GTLTVLPVAT AHPVVAGELN VGNSAYVVET LARACDGCLN GEFAALITGP 

       130        140        150        160        170        180 
VNKGVINDAG VPFIGHTEFF ADRSGCDRVV MMLATEELRV ALATTHLPLL AVPGAITRQS 

       190        200        210        220        230        240 
LHEVIRILDH DLKTKFGLAQ PQIYVCGLNP HAGEGGHMGR EEIDTIIPAL DELRAEGITL 

       250        260        270        280        290        300 
IGPLPADTLF QPKYLQHADA VLAMYHDQGL PVLKYQGFGR AVNITLGLPF IRTSVDHGTA 

       310        320        330 
LELAGTGTAD AGSFKTALNL AIKMIINCNE
A8G9P1 in FASTA format

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