ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry O55102


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name BL1S1_MOUSE
Primary accession number O55102
Secondary accession number Q9DC96
Integrated into Swiss-Prot on July 15, 1999
Sequence was last modified on January 4, 2005 (Sequence version 2)
Annotations were last modified on    June 16, 2009 (Entry version 45)
Name and origin of the protein
Protein name Biogenesis of lysosome-related organelles complex 1 subunit 1
Synonyms BLOC-1 subunit 1
GCN5-like protein 1
Gene name
Name: Bloc1s1
Synonyms: Gcn5l1
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=129/SvJ;
DOI=10.1016/S0378-1119(97)00486-1; PubMed=9426003 [NCBI, ExPASy, EBI, Israel, Japan]
Driessen C.A.G.G., Winkens H.J., Kuhlmann L.D., Janssen B.P.M., van Vught A.H.M., Deutman A.F., Janssen J.J.M.;
"Cloning and structural analysis of the murine GCN5L1 gene.";
Gene 203:27-31(1997).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J;
TISSUE=Brain;
DOI=10.1126/science.1112014; PubMed=16141072 [NCBI, ExPASy, EBI, Israel, Japan]
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J., Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6;
TISSUE=Eye;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
  • FUNCTION: May be involved in the biogenesis of specialized organelles of the endosomal-lysosomal system (By similarity).
  • SUBUNIT: Component of the biogenesis of lysosome-related organelles (BLOC-1) complex which is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system (By similarity).
  • SIMILARITY: Belongs to the BLOC1S1 family.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Y13778; CAA74108.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Y13779; CAA74108.1; JOINED; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Y13780; CAA74108.1; JOINED; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Y13781; CAA74108.1; JOINED; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK003035; BAB22523.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC034662; AAH34662.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
IPI IPI00115766; -.
PIR JC6514; JC6514.
RefSeq NP_056555.2; -.
UniGene Mm.30118
3D structure databases
ModBase O55102.
PTM databases
PhosphoSite O55102; -.
Organism-specific databases
MGI MGI:1195276; Bloc1s1.
Gene expression databases
Bgee O55102; -.
GermOnline ENSMUSG00000025349; Mus musculus.
Ontologies
GO
GO:0005829; Cellular component: cytosol (inferred from direct assay from MGI).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from MGI).
QuickGo view.
Family and domain databases
InterPro IPR009395; GCN5L1.
Graphical view of domain structure.
Pfam PF06320; GCN5L1; 1.
Pfam graphical view of domain structure.
Proteomic databases
PRIDE O55102; -.
Genome annotation databases
Ensembl ENSMUSG00000025349; Mus musculus. [Contig view]
GeneID 14533; -.
KEGG mmu:14533; -.
Phylogenomic databases
HOGENOM O55102; -.
HOVERGEN O55102; -.
OMA O55102; YVNQRKL.
Other
NextBio 286184; -.
SOURCE Bloc1s1; Mus musculus.
ProtoNet O55102.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Phosphoprotein.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   125  125     Biogenesis of lysosome-related organelles complex 1 subunit 1. PRO_0000156332
MOD_RES   107   107        Phosphothreonine (By similarity). 
CONFLICT   26    26        E -> Y (in Ref. 1; CAA74108). 
CONFLICT   35    35        T -> I (in Ref. 1; CAA74108). 
CONFLICT   40    40        D -> V (in Ref. 1; CAA74108). 
Sequence information
Length: 125 AA [This is the length of the unprocessed precursor] Molecular weight: 14281 Da [This is the MW of the unprocessed precursor] CRC64: 754897B17BC9479D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLSRLLKEHQ AKQNERKELQ EKRRREAIAA ATCLTEALVD HLNVGVAQAY MNQRKLDHEV 

        70         80         90        100        110        120 
KTLQVQAAQF AKQTGQWIGM VENFNQALKE IGDVENWARS IELDMRTIAT ALEYVYKGQL 


QSAPS 

O55102 in FASTA format

View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!