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UniProtKB/Swiss-Prot entry O05139

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name STHA_PSEFL
Primary accession number O05139
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 65)
Name and origin of the protein
Protein name Soluble pyridine nucleotide transhydrogenase
Synonyms STH
EC 1.6.1.1
NAD(P)(+) transhydrogenase [B-specific]
Gene name
Name: sthA
Synonyms: sth
From
Pseudomonas fluorescens [TaxID: 294] 
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 2-26, AND CHARACTERIZATION.
STRAIN=NCIMB 9815;
PubMed=9098078 [NCBI, ExPASy, EBI, Israel, Japan]
French C.E., Boonstra B., Bufton K.A.J., Bruce N.C.;
"Cloning, sequence, and properties of the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens.";
J. Bacteriol. 179:2761-2765(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U91523; AAB50562.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
HSSP P14218; 1LPF. [HSSP ENTRY / PDB]
ModBase O05139.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0003957; Molecular function: NAD(P)+ transhydrogenase (B-specific) activity (inferred from electronic annotation from HAMAP).
GO:0006739; Biological process: NADP metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00247; -; 1.
PBIL [Tree]
InterPro IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR000815; Hg_reductase.
IPR001100; Pyr_nuc-diS_OxRdtase.
IPR004099; Pyr_nucl-diS_OxRdtase_dimer.
IPR001327; Pyr_OxRdtase_NAD_bd.
Graphical view of domain structure.
Gene3D G3DSA:3.30.390.30; Pyr_redox_dim; 1.
Pfam PF00070; Pyr_redox; 1.
PF07992; Pyr_redox_2; 1.
PF02852; Pyr_redox_dim; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00945; HGRDTASE.
PR00411; PNDRDTASEI.
ProDom PD000139; FAD_pyr_redox; 1.
[Domain structure / List of seq. sharing at least 1 domain]
BLOCKS O05139.
Other
ProtoNet O05139.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cytoplasm; Direct protein sequencing; FAD; Flavoprotein; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   464  463     Soluble pyridine nucleotide transhydrogenase. PRO_0000068069
NP_BIND   35    44  10     FAD (By similarity). 
CONFLICT   26    26        K -> D (in Ref. 1; AA sequence). 
CONFLICT   26    26        K -> R (in Ref. 1; AA sequence). 
Sequence information
Length: 464 AA [This is the length of the unprocessed precursor] Molecular weight: 51008 Da [This is the MW of the unprocessed precursor] CRC64: 333D7F4EABB6944F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAVYNYDVVV LGSGPAGEGA AMNAAKAGRK VAMVDSRRQV GGNCTHLGTI PSKALRHSVR 

        70         80         90        100        110        120 
QIMQFNTNPM FRAIGEPRWF SFPDVLKSAE KVISKQVASR TGYYARNRVD LFFGTGSFAD 

       130        140        150        160        170        180 
EQTVEVVCAN GVVEKLVAKH IIIATGSRPY RPADIDFHHP RIYDSDTILS LGHTPRKLII 

       190        200        210        220        230        240 
YGAGVIGCEY ASIFSGLGVL VELVDNRDQL LSFLDSEISQ ALSYHFSNNN ITVRHNEEYD 

       250        260        270        280        290        300 
RVEGLDNGVI LHLKSGKKIK ADALLWCNGR TGNTDKLGME NIGVKVNSRG QIEVDENYRT 

       310        320        330        340        350        360 
CVTNIYGAGD VIGWPSLASA AHDQGRSAAG SIVDNGSWRY VNDVPTGIYT IPEISSIGKN 

       370        380        390        400        410        420 
EHELTKAKVP YEVGKAFFKS MARAQIAGEP QGMLKILFHR ETLEVLGVHC FGYQASEIVH 

       430        440        450        460 
IGQAIMNQPG EQNTLKYFVN TTFNYPTMAE AYRVAAYDGL NRLF
O05139 in FASTA format

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