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UniProtKB/Swiss-Prot entry O14121


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NDH1_SCHPO
Primary accession number O14121
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 50)
Name and origin of the protein
Protein name Probable NADH-ubiquinone oxidoreductase C3A11.07, mitochondrial [Precursor]
Synonym EC 1.6.5.3
Gene name
ORFNames: SPAC3A11.07
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[2]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1038/nbt1222; PubMed=16823372 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.;
"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.";
Nat. Biotechnol. 24:841-847(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329670; CAB16382.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T11629; T11629.
RefSeq NP_594196.1; -.
3D structure databases
ModBase O14121.
Organism-specific databases
GeneDB_Spombe SPAC3A11.07; -.
Gene expression databases
ArrayExpress O14121; -.
Ontologies
GO
GO:0005739; Cellular component: mitochondrion (inferred from direct assay from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR001327; Pyr_OxRdtase_NAD_bd.
Graphical view of domain structure.
Pfam PF00070; Pyr_redox; 1.
PF07992; Pyr_redox_2; 1.
Pfam graphical view of domain structure.
BLOCKS O14121.
Genome annotation databases
GeneID 2543119; -.
KEGG spo:SPAC3A11.07; -.
Other
ProtoNet O14121.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; Mitochondrion; NAD; Oxidoreductase; Transit peptide; Ubiquinone.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1    37  37     Mitochondrion (Potential). 
CHAIN   38   551  514     Probable NADH-ubiquinone oxidoreductase C3A11.07, mitochondrial. PRO_0000337257
NP_BIND   93   123  31     FAD (By similarity). 
NP_BIND   255   291  37     NAD (By similarity). 
Sequence information
Length: 551 AA [This is the length of the unprocessed precursor] Molecular weight: 61675 Da [This is the MW of the unprocessed precursor] CRC64: FED02DB71DEB9281 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLFSRSILRG MPKAGIPKSP LALSASRNLR LANSVRFASD AASSPKSTTS KWKILKRTTL 

        70         80         90        100        110        120 
GLFATAVVLY GANVYRFRHP DPHQPLPDPS KKTLVVLGAG WGATSILRTI DTSLFNVIVV 

       130        140        150        160        170        180 
SPRNYFLFTS LLPSTATGSV HTRSIVQPIR YMLRHKSCYV KFYEAECTDV DADKKVIHIK 

       190        200        210        220        230        240 
KTTTDGVDLE QEIKYDYLVC SHGAETQTFN IPGIAEYGCF LKEIWDAQKI RARILHCLEQ 

       250        260        270        280        290        300 
AQFKDLPAET RRRYVHTVVV GGGPTGMEFA GEMADFIEDD LKSWYPELAD DFAVTLVEAL 

       310        320        330        340        350        360 
PSVLPMFSAK LRDYTQSLFD SSHIKIRTNT ALKKVTAENI HVEVKNPDGS KQEEVIPYGL 

       370        380        390        400        410        420 
LVWAGGNRAR PLTKKLMEGS EEQNNRRGLV VDEYLKLKGY KDIFALGDCT HTAYAPTAQV 

       430        440        450        460        470        480 
ASQQGAYLGQ LFNKLGSLNF EKPSEDRHIA LGDEMDSSTL ISLANEKHAS TKVFLPFKYS 

       490        500        510        520        530        540 
HQGSLAYVGH EKAIADIEVP WFGKQLHASG ALAFYFWRSV YLSELYSLRN RTNVTLDWIR 

       550 
VKLFGRDISS L 

O14121 in FASTA format

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