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UniProtKB/Swiss-Prot entry O34354


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UXAB_BACSU
Primary accession number O34354
Secondary accession numbers None
Integrated into Swiss-Prot on July 11, 2003
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 45)
Name and origin of the protein
Protein name Altronate oxidoreductase
Synonyms EC 1.1.1.58
Tagaturonate reductase
Tagaturonate dehydrogenase
Gene name
Name: uxaB
Synonyms: yjmI
OrderedLocusNames: BSU12380
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
PubMed=9579062 [NCBI, ExPASy, EBI, Israel, Japan]
Rivolta C., Soldo B., Lazarevic V., Joris B., Mauel C., Karamata D.;
"A 35.7 kb DNA fragment from the Bacillus subtilis chromosome containing a putative 12.3 kb operon involved in hexuronate catabolism and a perfectly symmetrical hypothetical catabolite-responsive element.";
Microbiology 144:877-884(1998).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF015825; AAC46334.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99110; CAB13095.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C69853; C69853.
RefSeq NP_389120.1; -.
3D structure databases
ModBase O34354.
Enzyme and pathway databases
BioCyc BSUB224308:BSU1239-MON; -.
Organism-specific databases
SubtiList BG13212; uxaB. [Micado]
Ontologies
GO
GO:0009026; Molecular function: tagaturonate reductase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00670; -; 1.
PBIL [Tree]
InterPro IPR013328; DHase_multihelical.
IPR013118; Mannitol_DHase_C.
IPR000669; Mannitol_DHase_core.
IPR013131; Mannitol_DHase_N.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF01232; Mannitol_dh; 1.
PF08125; Mannitol_dh_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00084; MTLDHDRGNASE.
BLOCKS O34354.
Genome annotation databases
GeneID 936468; -.
GenomeReviews AL009126_GR; BSU12380.
KEGG bsu:BSU12380; -.
NMPDR fig|224308.1.peg.1239; -.
Phylogenomic databases
HOGENOM O34354; -.
Genome annotation databases
CMR O34354; BSU12380.
Other
ProtoNet O34354.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   480  480     Altronate oxidoreductase. PRO_0000170739
NP_BIND   19    30  12     NAD (By similarity). 
Sequence information
Length: 480 AA [This is the length of the unprocessed precursor] Molecular weight: 55361 Da [This is the MW of the unprocessed precursor] CRC64: DC7DBC8DA500F8D4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MQKLNKNVYD HYTQYPEKIL QFGEGNFLRG FIDWQIDQLN QHTDFNGSVA VVQPRGSEKI 

        70         80         90        100        110        120 
KRLNEQDGLY TLFLQGMKDG EAVNEHMIIN SISRGIDLFS DYEAYKELAS SERLRFIISN 

       130        140        150        160        170        180 
TTEAGIVCDE KDRLEDRPQK TFPGKLTAFL YFRYQAFKGD QTKGCVLIPC ELIENNGEKL 

       190        200        210        220        230        240 
RETVLHYAHL WKLEEGFTQW IHEANTFCNS LVDRIVPGFP VDSIDEITAD LGYQDDLIVV 

       250        260        270        280        290        300 
GEQYYLWVIE GPDWIGKELP FAAAGLHTKI VSDLTPYRTK KVRILNGAHT AMTPVALLYG 

       310        320        330        340        350        360 
LKTVRDAVEH PEVGRFIREL IDDEILPVLK MEGLSQYADD VLNRFKNPYI KHYLESIALN 

       370        380        390        400        410        420 
AISKFKTRNL PTLKEYAEQK GQLPERLVFS FSALLYFYHD NETLQDDPAV LQFFKEVWCQ 

       430        440        450        460        470        480 
EDGDMLRIAS RVLGEQRLWG ADLNEIPKLT DRVAVYLNHI HELGMQRALE QYCIQGGEVR 

O34354 in FASTA format

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