ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry O59651

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name CATA_HALMA
Primary accession number O59651
Secondary accession number Q5V2Y1
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 71)
Name and origin of the protein
Protein name Peroxidase/catalase
Synonyms EC 1.11.1.6
EC 1.11.1.7
Catalase-peroxidase
Gene name
Name: perA
Synonyms: katG2
OrderedLocusNames: rrnAC1171
From
Haloarcula marismortui (Halobacterium marismortui) [TaxID: 2238] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Haloarcula.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE, AND MASS SPECTROMETRY.
DOI=10.1016/S0300-9084(99)80005-4; PubMed=9924978 [NCBI, ExPASy, EBI, Israel, Japan]
Cannac-Caffrey V., Hudry-Clergeon G., Petillot Y., Gagnon J., Zaccai G., Franzetti B.;
"The protein sequence of an archaeal catalase-peroxidase.";
Biochimie 80:1003-1011(1998).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 43049 / DSM 3752 / JCM 8966;
DOI=10.1101/gr.2700304; PubMed=15520287 [NCBI, ExPASy, EBI, Israel, Japan]
Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V.;
"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea.";
Genome Res. 14:2221-2234(2004).
[3]
 X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 19-731.
DOI=10.1038/nsb834; PubMed=12172540 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada Y., Fujiwara T., Sato T., Igarashi N., Tanaka N.;
"The 2.0 A crystal structure of catalase-peroxidase from Haloarcula marismortui.";
Nat. Struct. Biol. 9:691-695(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Y16851; CAA76423.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY596297; AAV46121.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T44846; T44846.
RefSeq YP_135827.1; -.
3D structure databases
PDB
1ITK; X-ray; 2.00 A; A/B=1-731.[ExPASy / RCSB / EBI]
PDBsum 1ITK; -.
ModBase O59651.
Protein family/group databases
PeroxiBase 2440; HmaCP01.
Enzyme and pathway databases
BioCyc HMAR272569:RRNAC1171-MON; -.
Family and domain databases
InterPro IPR000763; Catalase_proxase.
IPR002016; Haem_peroxidase_pln/fun/bac.
Graphical view of domain structure.
Pfam PF00141; peroxidase; 2.
Pfam graphical view of domain structure.
PRINTS PR00460; BPEROXIDASE.
PR00458; PEROXIDASE.
TIGRFAMs TIGR00198; cat_per_HPI; 1.
PROSITE PS00435; PEROXIDASE_1; 1.
PS00436; PEROXIDASE_2; 1.
PS50873; PEROXIDASE_4; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS O59651.
Genome annotation databases
GeneID 3129320; -.
GenomeReviews AY596297_GR; rrnAC1171.
KEGG hma:rrnAC1171; -.
NMPDR fig|272569.1.peg.1095; -.
Phylogenomic databases
HOGENOM O59651; -.
Genome annotation databases
CMR O59651; rrnAC1171.
Other
ProtoNet O59651.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Complete proteome; Direct protein sequencing; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   731  730     Peroxidase/catalase. PRO_0000055580
ACT_SITE   96    96        Proton acceptor. 
METAL   259   259        Iron (heme axial ligand). 
SITE   92    92  1     Transition state stabilizer. 
CROSSLNK   95   218        Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-244). 
CROSSLNK   218   244        Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-95). 
HELIX   23    26  4      
HELIX   34    37  4      
HELIX   52    58  7      
HELIX   61    72  12      
HELIX   82    84  3      
HELIX   87    98  12      
TURN   103   105  3      
HELIX   114   116  3      
HELIX   120   122  3      
HELIX   124   126  3      
HELIX   129   135  7      
HELIX   137   143  7      
HELIX   144   146  3      
HELIX   149   163  15      
STRAND   217   219  3      
HELIX   224   226  3      
HELIX   230   242  13      
TURN   243   245  3      
HELIX   248   258  11      
STRAND   266   268  3      
HELIX   270   273  4      
HELIX   278   280  3      
HELIX   283   285  3      
STRAND   303   306  4      
STRAND   309   314  6      
HELIX   321   328  8      
STRAND   331   335  5      
STRAND   341   348  8      
TURN   349   352  4      
HELIX   370   377  8      
HELIX   379   390  12      
HELIX   392   408  17      
HELIX   414   416  3      
HELIX   428   430  3      
HELIX   443   455  13      
HELIX   460   471  12      
TURN   476   479  4      
HELIX   487   489  3      
HELIX   493   495  3      
HELIX   497   499  3      
HELIX   501   521  21      
STRAND   524   526  3      
HELIX   530   548  19      
HELIX   566   568  3      
HELIX   571   574  4      
HELIX   575   577  3      
STRAND   580   582  3      
TURN   583   586  4      
HELIX   596   606  11      
HELIX   611   624  14      
HELIX   628   630  3      
HELIX   646   652  7      
STRAND   656   660  5      
STRAND   665   672  8      
TURN   673   675  3      
STRAND   678   683  6      
HELIX   684   687  4      
HELIX   688   690  3      
HELIX   693   702  10      
HELIX   708   724  17      
HELIX   728   730  3      
Sequence information
Length: 731 AA [This is the length of the unprocessed precursor] Molecular weight: 81384 Da [This is the MW of the unprocessed precursor] CRC64: 0E12DE0CF72FF3A3 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAETPNSDMS GATGGRSKRP KSNQDWWPSK LNLEILDQNA RDVGPVEDDF DYAEEFQKLD 

        70         80         90        100        110        120 
LEAVKSDLEE LMTSSQDWWP ADYGHYGPLF IRMAWHSAGT YRTADGRGGA AGGRQRFAPI 

       130        140        150        160        170        180 
NSWPDNANLD KARRLLLPIK QKYGQKISWA DLMILAGNVA IESMGFKTFG YAGGREDAFE 

       190        200        210        220        230        240 
EDKAVNWGPE DEFETQERFD EPGEIQEGLG ASVMGLIYVN PEGPDGNPDP EASAKNIRQT 

       250        260        270        280        290        300 
FDRMAMNDKE TAALIAGGHT FGKVHGADDP EENLGPEPEA APIEQQGLGW QNKNGNSKGG 

       310        320        330        340        350        360 
EMITSGIEGP WTQSPTEWDM GYINNLLDYE WEPEKGPGGA WQWAPKSEEL KNSVPDAHDP 

       370        380        390        400        410        420 
DEKQTPMMLT TDIALKRDPD YREVMETFQE NPMEFGMNFA KAWYKLTHRD MGPPERFLGP 

       430        440        450        460        470        480 
EVPDEEMIWQ DPLPDADYDL IGDEEIAELK EEILDSDLSV SQLVKTAWAS ASTYRDSDKR 

       490        500        510        520        530        540 
GGANGARLRL EPQKNWEVNE PEQLETVLGT LENIQTEFND SRSDGTQVSL ADLIVLGGNA 

       550        560        570        580        590        600 
AVEQAAANAG YDVEIPFEPG RVDAGPEHTD APSFDALKPK VDGVRNYIQD DITRPAEEVL 

       610        620        630        640        650        660 
VDNADLLNLT ASELTALIGG MRSIGANYQD TDLGVFTDEP ETLTNDFFVN LLDMGTEWEP 

       670        680        690        700        710        720 
AADSEHRYKG LDRDTGEVKW EATRIDLIFG SNDRLRAISE VYGSADAEKK LVHDFVDTWS 

       730 
KVMKLDRFDL E
O59651 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ca flag CBR Canada Mirror sites: Australia Brazil China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!